Publications

2023

393) “Phosphorylation Sites of the Gastric Inhibitory Polypeptide Receptor (GIPR) Revealed by Trapped-Ion-Mobility Spectrometry Coupled to Time-of-Flight Mass Spectrometry (TIMS-TOF MS),” K. A. Brown, R. K. Morris, S. J. Eckhardt, Y. Ge, S. H. Gellman. J. Am. Chem. Soc. 2023, 145 (51) 28030–28037.

392) “Thioamide Analogues of MHC I Antigen Peptides,” R. Gibadulliln, R. K. Morris, J. Niu, J. Sidney, A. Sett, S. H. Gellman. J. Am. Chem. Soc. 2023, 145 (47) 25559–25569. 

391) “Effects of Replacing a Central Glycine Residue in GLP-1 on Receptor Affinity and Signaling Profile,” K. A. Brown and S. H. Gellman ChemBioChem 2023, in press.

390) “Harnessing Aromatic-Histidine Interactions through Synergistic Backbone Extension and Side Chain Modification,” Z. Yu, D. F. Kreitler, Y. T. T. Chiu, R. Xu, A. T. Bruchs, C. A. Bingman and S. H. Gellman Angew. Chem. Int. Ed. 202362, e202308100.

389) “Hormone Analogues with Unique Signaling Profiles from Replacement of α Residue Triads with β/γ Diads,” R. Gibadullin, T. W. Kim, L. M.-L. Tran and S. H. Gellman J. Am. Chem. Soc.2023145, 20539.

388) “Differential Membrane Binding of α/β-Peptide Foldamers: Implications for Cellular Delivery and Mitochondrial Targeting,” T.-H. Lee, J. W. Checco, T. Malcom, C. H. Eller, R. T. Raines, S. H. Gellman, E. F. Lee, W. D. Fairlie and M.-I. Aguilar Aust. J. Chem. 202376, 482.

387) “Differential Responses of the GLP-1 and GLP-2 Receptors to N-Terminal Modification of a Dual Agonist.” Gibadullin, R.; Cary, B. P.; Gellman, S. H.; J. Am. Chem. Soc. 2023, 145, 12105.

386) “Interactions of SARS-CoV-2 and MERS-CoV fusion peptides measured using single-molecule force methods.” Qiu, C.; Whittaker, G. R.; Gellman, S. H.; Daniel, S.;  Abbot, N. L.; Biophysical Journal2023, 122, 646–660.

2022

385) “Kinetic and Thermodynamic Insights into Agonist Interactions with the Parathyroid Hormone Receptor-1 from a New NanoBRET Assay.” Yu, Z.; Cary, B. P.; Kim, T. W.; Nguyen, K. D.; Gardella, T. J.; Gellman, S. H. ACS Chem. Biol. 2022, 17, 11, 3148–315.

384) “Altered signaling at the PTH receptor via modified agonist contacts with the extracellular domain provides a path to prolonged agonism in vivo.” Liu, S.; Yu, Z.; Daley, E. J.; Bingman, C. A.; Bruchs, A. T.; Gardella, T. J.; Gellman, S. J. PNAS. 2022, 119 (48), e2212736119.

383) “Formation of versus Recruitment to RNA-Rich Condensates: Controlling Effects Exerted by Peptide Side Chain Identity.”
Niu, J.; Qiu, C.; Abbott, N. L.; Gellman, S. J. Am. Chem. Soc. 2022, 144, 10386.

382) “Trimer-to-Monomer Disruption Mechanism for a Potent, Protease-Resistant Antagonist of Tumor Necrosis Factor-α Signaling.” Niu, J.; Cederstrand, A. J.; Eddinger, G. A.; Yin, B.; Checco, J. W.; Bingman, C. A.; Outlaw, V. K.; Gellman, S. J. Am. Chem. Soc. 2022, 144, 9610.

381) “Tailoring Reaction Selectivity by Modulating a Catalytic Diad on a Foldamer Scaffold.” Andrews, M. K.; Liu, X.; Gellman, S. H. J. Am. Chem. Soc. 2022, 144, 5, 2225-2232.

380) “Secondary Amine Pendant β-Peptide Polymers Displaying Potent Antibacterial Activity and Promising Therapeutic Potential in Treating MRSA-Induced Wound Infections and Keratitis.” Qian, Y.; Deng, S.; Cong, Z.; Zhang, H.; Lu, Z.; Shao, N.; Bhatti, S. A.; Zhou, C.; Cheng, J.; Gellman, S. H.; Liu, R. J. Am. Chem. Soc. 2022, 144, 4, 1690-1699.

379) “Structural and functional diversity among agonist-bound states of the GLP-1 receptor.” Cary, B. P.; Deganutti, G.; Zhao, P.; Truong, T. T.; Piper, S. J.; Liu, X.; Belousoff, M. J.; Danev, R.; Sexton, P M.; Wootten, D.; Gellman, S. H. Nature Chem Bio 2022, 18, 256-263.

2021

378) “Local rigidification and possible coacervation of the Escherichia coli DNA by cationic nylon-3 polymers.” Zhu, Y.; Lei, L.; Mustafi, M.; Rank, L. A.; Gellman, S. H.; Weisshaar, J. C. Biophysical Journal 2021, 120, 23, 5243-5254.

377) “Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation.” White, A. D.; Peña, K. A.; Clark, L. J.; Maria, C. S.; Liu, S.; Jean-Alphonse, F. G.; Lee, J. Y.; Lei, S.; Cheng, Z.; Tu, C.; Fang, F.; Szeto, N.; Gardella, T. J.; Gellman, S. H.; Bahar, I.; Sutkeviciute, I.; Chang, W.; Vilardaga, J. Science Signaling 2021, 14, 703, eabc5944.

376) “Comparisons of β‐Hairpin Propensity Among Peptides with Homochiral or Heterochiral Strands.” Liu, X.; Gellman, S. H. ChemBioChem 2021, 22, 18, 2772-2776.

375) “Conformationally flexible core-bearing detergents with a hydrophobic or hydrophilic pendant: Effect of pendant polarity on detergent conformation and membrane protein stability.” Sadaf, A.; Kim, S.; Bae, H. E.; Wang, H.; Nygaard, A.; Uegaki, Y.; Du, Y.; Munk, C. F.; Katsube, S.; Lee, H. S.; Bae, J.; Choi, C. W.; Choi, H.l Byrne, B.; Gellman, S. H.; Guan, L.; Loland, C. J.; Kobilka, B. K.; Chae, P. S. Acta Bio. 2021, 128, 393-407.

374) “Versatile Open-Source Photoreactor Architecture for Photocatalysis Across the Visible Spectrum.” Lampkin, P. P.; Thompson, B. J.; Gellman, S. H. Org. Lett. 2021, 23, 13, 5277-5281.

373) “Potential Foldamers Based on an ortho-Terphenyl Amino Acid.” Kleman, A. F.; Dufek, D. L.; Fobe, T. L.; McCaslin, D. R.; Cary, B. P.; Shirts, M. R.; Gellman, S. H. Org. Lett. 2021, 23, 12, 4855-4859.

372) “Conformationally flexible core-bearing detergents with a hydrophobic or hydrophilic pendant: Effect of pendant polarity on detergent conformation and membrane protein stability.” Sadaf, A.; Kim, S.; Bae, H. E.; Wang, H.; Nygaard, A.; Uegaki, Y.; Du, Y.; Munk, C. F.; Katsube, S.; Lee, H. S.; Bae, J.; Choi, C. W.; Choi, H.; Byrne, B.; Gellman, S. H.; Guan, L.; Loland, C. J.; Kobilka, B. K.; Im, W.; Chae, P. S.  Acta. Biomater. 2021, 128, 1, 393-407.

371) “Backbone Modifications of HLA-A2-Restricted Antigens Induce Diverse Binding and T Cell Activation Outcomes.” Gibadullin, R.; Randall, C. J.; Sette, A.; Gellman, S. H. J. Am. Chem. Soc. 2021, 143, 17, 6470-6481.

370) “Engineering protease-resistant peptides to inhibit human parainfluenza viral respiratory infection.” Outlaw, V. K.; Cheloha, R. W.; Jurgens, E. M.; Bovier, F. T.; Zhu, Y.; Kreitler, D. F.; Harder, O.; Niewiesk, S.; Porotto, M.; Gellman, S. H.; Moscona, A. J. Am. Chem. Soc. 2021, 143, 15, 5958-5966.

369) “Stable Picodisc Assemblies from Saposin Proteins and Branched Detergents.” Kurgan, K. W.; Chen, B.; Brown, K. A.; Cobra, P. F.; Ye, X.; Ge, Y.; Gellman, S. H. Biochemistry, 2021, 60, 14, 1108-1119.

368) “Cationic Homopolymers Inhibit Spore and Vegetative Cell Growth of Clostridioides difficile.” Jones, J. B.; Liu, L.; Rank, L. A.; Wetzel, D.; Woods, E. C.; Biok, N.; Anderson, S. E.; Lee, M.; Liu, R.; Huth, S.; Sandhu, B. K.; Gellman, S. H.; McBride, S. M. ACS Infect. Dis. 2021, 7, 5, 1236-1247.

367) “Cationic Side Chain Identity Directs the Hydrophobically Driven Self-Assembly of Amphiphilic β-Peptides in Aqueous Solution.” Wang, C.; Biok, N. A.; Nayani, K.; Wang, X.; Yeon, H.; Ma, C. D; Gellman, S. H.; Abbot, N. L. Langmuir, 2021, 37, 11, 3288-3298.

366) “Beyond Amphiphilic Balance: Changing Subunit Stereochemistry Alters the Pore-Forming Activity of Nylon‑3 Polymers.” Liu, L.; Courtney, K. C.; Huth, S. W.; Rank, L. A.; Weisblum, B.; Chapman, E. R.; Gellman, S. H. J. Am. Chem. Soc. 2021, 143, 8, 3219-3230.

365) “Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets.” de Vries, R. D.; Schmitz, K. S.; Bovier, F. T.; Predella, C.; Khao, J.; Noack, D.; Haagmans, B. L.; Herfst, S.; Stearns, K. N.; Drew-Bear, J.; Biswas, S.; Rock, B.; McGill, G.; Dorrello, N. V.; Gellman, S. H.; Alabi, C. A.; de Swart, R. L.; Moscona, A.; Porotto, M. Science, 2021, 371, 6536, 1379-1382.

2020

364) “Diverse Impacts on Prokaryotic and Eukaryotic Membrane Activities from Hydrophobic Subunit Variation Among Nylon-3 Copolymers.” Rank, L. A.; Agrawal, A.; Liu, L.; Zhu, Y.; Mustafi, M.; Weisshaar, J. C.; Gellman, S. H. ACS Chem. Bio. 2021, 16, 1, 176-184.

363) “Harnessing Noncovalent Interactions to Drive Single-Chain Nanoparticle Formation.” Liu, L.; Gellman, S. H. Macromolecules, 2020, 53, 19, 2140-2144.

362) “Foldamer Catalysis. Girvin, Z. C.; Gellman, S. H. J. Am. Chem. Soc. 2020, 142, 17211–17223.

361) “Inhibition of Coronavirus Entry In Vitro and Ex Vivo by a Lipid-Conjugated Peptide Derived from the SARS-CoV-2 Spike Glycoprotein HRC Domain.” Outlaw, V. K.; Bovier, F. T.; Mears, M. C.; Cajimat, M. N.; Zhu, Y.; Lin, M. J.; Addetia, A.; Lieberman, N. A. P.; Peddu, V.; Xie, X.; Shi, P.; Greninger, A. L. ; Gellman, S. H. ; Bente, D. A. ; Moscona, A. ; Porotto, M. MBIO 2020, 11, 5, e01935-20.

360) Tumor Necrosis Factor-α Trimer Disassembly and Inactivation via Peptide-Small Molecule Synergy.” Checco,  J. W.; Eddinger, G. A.; Rettko, N. J.; Chartier, A. R.; Gellman, S. H. ACS Chem. Biol. 2020, 15, 8, 2116–2124.

359) Effects of Single α-to-β Residue Replacements on Recognition of an Extended Segment in a Viral Fusion Protein.” Outlaw, V. K.; Kreitler, D. F.; Stelitano, D.; Porotto, M.; Moscona, A.; Gellman, S. H. ACS Infect. Dis. 2020, 6, 8, 2017–2022

358) “Catalytic Intramolecular Conjugate Additions of Aldehyde-Derived Enamines to α,β-Unsaturated Esters.” Girvin, Z. C.; Lampkin, P. P.; Liu, X.; Gellman S. H. Org. Lett. 2020, 22, 4568–4573.

357) “Gq/11-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR.” White, A. D.; Jean-Alphonse, F. G.; Fang, F.; Peña, K. A.; Liu, S.; König, G. M.;Inoue, A.;Aslanoglou, D.; Gellman, S. H.; Kostenis, E.;Xiao, K.; Vilardaga, J.

356) “Influence of immobilized cations on the thermodynamic signature of hydrophobic interactions at chemically heterogeneous surfaces.” Yeon, H.; Wang, C.; Gellman, S. G.; Abbott, N. L. Mol. Syst. Des. Eng., 2020, 5, 835846.

355) “Structure-Guided Improvement of a Dual HPIV3/RSV Fusion Inhibitor.” Outlaw, V. K.; Lemke, J. T.;  Zhu, Y.; Gellman, S. H.; Porotto, M.; Moscona, A. J. Am. Chem. Soc. 2020, 142, 2140–2144.

354) “Preparation of β2-Homologous Amino Acids Bearing Polar Side Chains via a Collective Synthesis Strategy.” Liu, S.; Gellman, S. H.  J. Org. Chem. 2020, 85, 1718–1724.

2019

353) “Foldamer-templated catalysis of macrocycle formation.” Girvin, Z. C.; Andrews, M. K.; Liu, X.; Gellman, S. H. Science 2019, 366, 1528-1531.

352) “Retention of Coiled-Coil Dimer Formation in the Absence of Ion Pairing at Positions Flanking the Hydrophobic Core.” Biok. N. A.; Passow, A. D.; Wang, C.; Bingman, C. A.; Abbott, N. L.; Gellman, S. H. Biochemistry 2019, 58, 4821-4826.

351) Use of Backbone Modification To Enlarge the Spatiotemporal Diversity of Parathyroid Hormone Receptor-1 Signaling via Biased Agonism.” Liu, S.; Jean-Alphonse, F. G.; White, A. D.; Wootten, D.; Sexton, P. M.; Gardella, T. J.; Vilardaga, J. P.; Gellman, S. H. J. Am. Chem. Soc. 2019, 141, 14486-14490.

350) “Recognition of Class II MHC Peptide Ligands That Contain ß-Amino Acids.” Cheloha, R.W.; Woodham, A.W.; Bousbaine, D.; Wang, T.; Liu, S.; Sidney, J.; Sette, A.; Gellman, S.H.; Ploegh, H.L. J. Immunol. 2019, 203, 1619-1628.

349) “Ketones from Nickel‐Catalyzed Decarboxylative, Non‐Symmetric Cross‐Electrophile Coupling of Carboxylic Acid Esters.” Wang, J.; Cary, B.P.; Beyer, P. D.; Gellman, S.H.; Weix, D.J. Angew. Chem. Int. Ed. Engl. 2019, 58, 12081-12085.

348) “Dual Inhibition of Human Parainfluenza Type 3 and Respiratory Syncytial Virus Infectivity with a Single Agent.” Outlaw, V. K.; Bottom-Tanzer, S.; Kreitler, D.F.; Gellman, S.H.; Porotto, M.; Moscona, M. J. Am. Chem. Soc. 2019, 141, 3212648-12656.

347) “Impact of substitution registry on receptor‐activation profiles of backbone‐modified glucagon‐like peptide‐1 analogues.” Cary, B.P.; Hager, M. V.; Gellman, S.H. ChemBioChem 2019, 20, 2834-2840.

346) “Retention of Native Quaternary Structure in Racemic Melittin Crystals.” Kurgan, K.W.; Kleman, A.F.; Bingman C.A.; Kreitler, D.F.; Weisblum, B.; Forest, K.T.; Gellman, S.H. J. Am. Chem. Soc. 2019, 141, 7704-7708.

345) “Use of a Stereochemical Strategy To Probe the Mechanism of Phenol-Soluble Modulin α3 Toxicity.” Yao, Z.; Cary, B.P.;  Bingman C.A.; Wang, C.; Kreitler, D.F.;  Satyshur, K.A.; Forest, K.T.; Gellman, S.H. J. Am. Chem. Soc. 2019, 141, 7660-7664.

344) “A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation.” Kreitler, D.F.; Yao, Z.;  Steinkruger, J.D.; Mortenson, D.E.; Huang, L.; Mittal, R.; Travis, B.R.; Forest, K.T.; Gellman, S.H. J. Am. Chem. Soc. 2019141, 1583–1592.

2018

343) “Receptor selectivity from minimal backbone modification of a polypeptide agonist.” Liu, S.; Cheloha, R.W.; Watanabe, T.; Gardella, T.J.; Gellman, S.H. Proc. Natl. Acad. Sci. U.S.A. 2018, 115, 12383-12388.

342) “Exploration of Diverse Reactive Diad Geometries for Bifunctional Catalysis via Foldamer Backbone Variation.” Girvin, Z.C.; Gellman, S.H. J. Am. Chem. Soc. 2018140, 12476–12483.

341) “Differential Effects of β3- vs. β2-Amino Acid Residues on the Helicity and Recognition Properties of Bim BH3-Derived α/β-Peptides.”  Eddinger, G.A.;  Gellman S.H. Angew. Chem. Int. Ed. Engl. 2018, 57, 13829-13832.

340) “Thermodynamic Scale of β‑Amino Acid Residue Propensities for an α‑Helix-like Conformation.” Fisher, B. F.; Hong, S.H.; Gellman, S.H. J. Am. Chem. Soc. 2018, 140, 9396–9399.

339) “Peptide-Like Nylon-3 Polymers with Activity against Phylogenetically Diverse, Intrinsically Drug-Resistant Pathogenic Fungi.” Rank, L.M.; Walsh, N.M.; Lim F.Y.; Gellman S.H.; Keller, N.P.; Hull, C.M. mSphere 20183, e00223-18.

338) “Impact of Backbone Pattern and Residue Substitution on Helicity in α/β/γ-Peptides.” Shin, H.Y.; Gellman, S.H. J. Am. Chem. Soc. 2018140, 1394–1400.

337) “Evaluation of β-Amino Acid Replacements in Protein Loops: Effects on Conformational Stability and Structure.” Mortenson, D. E.; Kreitler, D. F.; Thomas, N. C.; Guzei, I. A.; Gellman, S.H.; Forest, K. T. ChemBioChem  201819, 604-612.

2017

336) “Non-Additive Interactions Mediated by Water at Chemically Heterogeneous Surfaces: Non-ionic Polar Groups and Hydrophobic Interactions.” Wang, C.; Ma, C. D.; Yeon, H.; Wang, X.; Gellman, S. H.; Abbott, N. L. J. Am. Chem. Soc. 2017, 139, 18536–18544.

335) “Toward a Soluble Model System for the Amyloid State.” Thomas, N. C.; Bartlett, G. J.; Woolfson, D. N.; Gellman, S.H. J. Am. Chem. Soc. 2017, 139, 16434–16437.

334) “Incorporation of β-peptides enhances the antifungal activity and selectivity of the helical antimicrobial peptide aurein 1.2.”  Lee, M. R.; Raman, N.; Gellman, S.H.; Lynn, D. M.; Palecek, S. P. ACS Chem. Biol. 2017, 12, 2975–2980.

333) “Development of Potent, Protease-Resistant Agonists of the Parathyroid Hormone Receptor with Broad β Residue Distribution.” Cheloha, R. W.; Chen, B.; Kumar, N. N.; Watanabe, T.; Thorne, R. G.; Li, L; Gardella, T. J.; Gellman, S.H. J. Med. Chem. 201760, 8816-8833.

332) “Helix Propensities of Amino Acid Residues via Thioester Exchange.” Fisher, B. F.; Hong, S.H.; Gellman, S.H. J. Am. Chem. Soc. 2017, 139, 13292–13295.

331) “A cationic polymer that shows high antifungal activity against diverse human pathogens.” Rank, L. A.; Walsh, N. M.; Liu, R.; Lim, F. Y.; Bok, J. W.; Huang, M.; Keller, N. P.; Gellman, S.H.; Hull, C. M. Antimicrob. Agents Chemother. 2017, 61, e00204-17.

330) “Inhibition of Ice Recrystallization by Nylon‑3 Polymers.” MacDonald, M. J.; Cornejo, N. R.; Gellman, S. H.; ACS Macro Lett. 2017, 6, 695-699.

329) “Characterization of signal bias at the GLP-1 receptor induced by backbone modification of GLP-1.” Hager, M. V.;  Clydesdale, L.; Gellman, S.H.; Sexton, P.M.; Wootten, D. Biochem. Pharmacol. 2017, 136, 99-108.

328) “Iterative non-proteinogenic residue incorporation yields α/β-peptides with a helix-loop-helix tertiary structure and high affinity for VEGF.” Checco, J.W.; Gellman, S.H. ChemBioChem. 2017, 18, 291-299.

2016

327) “β-Arrestin-Biased Agonists of the GLP-1 Receptor from β-Amino Acid Residue Incorporation into GLP-1 Analogues.” Hager, M. V.; Johnson, L. M.; Wootton, D.; Sexton, P. M.; Gellman, S.H. J. Am. Chem. Soc.  2016, 138, 14970-14979.

326) “Inherent Conformational Preferences of Ac-Gln-Gln-NHBn: Sidechain Hydrogen Bonding Supports a β-Turn in the Gas Phase.” Walsh, S. P.; Blodgett, K. N.; McBurney, C.; Gellman, S.H.; Zwier, T. S.; Angew. Chem. Int. Ed. Engl.  2016, 55, 14618-14622.

325) “Backbone Modification of a Parathyroid Hormone Receptor‑1 Antagonist/Inverse Agonist.” Cheloha, R.W.; Watanabe, T.; Dean, T.; Gellman, S.H.; Gardella, T. J. ACS Chem. Biol.  2016, 11, 2752.

324) “Impact of γ‑Amino Acid Residue Preorganization on α/γ-Peptide Foldamer Helicity in Aqueous Solution.” Fisher, B. F.; Gellman, S.H. J. Am. Chem. Soc.  2016, 138, 10766.

323) “Evaluation of the Ser-His Dipeptide, a Putative Catalyst of Amide and Ester Hydrolysis.” MacDonald, M.J.; Lavis, L.D.; Hilvert, D.; Gellman, S.H. Org. Lett. 2016, 18, 3518.

322) “Targeting recognition surfaces on natural proteins with peptidic foldamers.” Checco, J.W.; Gellman, S.H. Curr. Opin. Struct. Biol. 2016, 39, 96.

321) “Effects of Single α-to-β Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization.” Kreitler, D.F.; Mortenson, D.E.; Forest, K.F.; Gellman, S.H. J. Am. Chem. Soc. 2016138, 6498.

320) “Conformation-specific spectroscopy of capped Glutamine-containing peptides: Role of a single glutamine residue on peptide backbone preferences.” Walsh, P.S.; Dean, J.C.; McBurney, C.; Kang, H.; Gellman, S.H.; Zwier, T. Phys Chem. Chem. Phys. 201620, 11306.

319) “Interaction of the Hydrophobic Tip of an Atomic Force Microscope with Oligopeptides Immobilized Using Short and Long Tethers.” Ma, C.D.; Acevedo-Vélez, C.; Wang, C.; Gellman, S.H.; Abbott, N.L. Langmuir 2016, 32, 2985.

318) “Single-cell, Time-resolved Antimicrobial Effects of a Highly Cationic, Random Nylon-3 Copolymer on Live E. coli.” Choi, H.; Chakraborty, S.; Liu, R.; Gellman, S.H.; Weisshaar, J.C. ACS Chem. Biol. 201611, 113.

2015

317) “High-resolution structures of a heterochiral coiled-coil.” Mortenson, D.E.; Steinkruger, J.D.; Kreitler, D.F.; Perroni, D.V.; Sorenson, G.P.; Huang, L.; Mittal, R.; Yun ,H.G.; Travis, B.R.; Mahanthappa, M.K.; Forest, K.T.; Gellman, S.H. Proc. Natl. Acad. Sci. U.S.A. 2015112, 13144.

316) “Impact of Strand Number on Parallel β-Sheet Stability.” Kung, V.M.; Cornilescu, G.; Gellman, S.H. Angew. Chem. Int. Ed. Engl. 2015, 54,14336–14339.

315) “Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif.” Hayouka, Z.; Thomas, N.C.; Mortenson, D.E.; Satyshur, K.A.; Weisblum, B.; Forest, K.T.; Gellman, S.H. J. Am. Chem. Soc. 2015137, 11884.

314) “α/β-Peptide Foldamers Targeting Intracellular Protein–Protein Interactions with Activity in Living Cells.” Checco JW, Lee EF, Evangelista M, Sleebs NJ, Rogers K, Pettikiriarachchi A, Kershaw NJ, Eddinger GA, Belair DG, Wilson JL, Eller CH, Raines RT, Murphy WL, Smith BJ, Gellman SH, Fairlie D J. Am. Chem. Soc. 2015137, 11365.

313) “PTH receptor-1 signalling–mechanistic insights and therapeutic prospects.” Cheloha RW, Gellman SH, Vilardaga JP, Gardella TJ Nat. Rev. Endocrinol. 2015, 10.1038/nrendo.2015.139.

312) “Correlating antimicrobial activity and model membrane leakage induced by nylon-3 polymers and detergents.” Hovakeemian SG, Liu R, Gellman SH, Heerklotz H Soft Matter 201511, 6840.

311) “Heterogeneous H-bonding in a foldamer helix.” Fisher BF, Guo L, Dolinar BS, Guzei IA, Gellman SH. J. Am. Chem. Soc. 2015, 137, 6484.

310) “Residue-Based Preorganization of BH3-Derived α/β-Peptides: Modulating Affinity, Selectivity and Proteolytic Susceptibility in α-Helix Mimics..” Peterson-Kaufman KJ, Haase HS, Boersma MD, Lee EF, Fairlie WD, Gellman SH. ACS Chem. Biol. 2015, 10, 1667.

309) “A preorganized β-amino acid bearing a guanidinium side chain and its use in cell-penetrating peptides.” Demizu Y, Oba M, Okitsu K, Yamashita H, Misawa T, Tanaka M, Kurihara M, Gellman SH. Org. Biomol. Chem. 2015, 13, 5617.

308) “Targeting diverse protein-protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold.” Checco JW, Kreitler DF, Thomas NC, Belair DG, Rettko NJ, Murphy WL, Forest KT, Gellman SH. Proc. Natl. Acad. Sci. USA. 2015, 112, 4552.

307) “Nylon-3 polymers active against drug-resistant Candida albicans biofilms.” Liu R, Chen X, Falk SP, Masters KS, Weisblum B, Gellman SH. J. Am. Chem. Soc. 2015137, 2183.

306) “Modulation of hydrophobic interactions by proximally immobilized ions.” Ma CD, Wang C, Acevedo-Vélez C, Gellman SH, Abbott NL. Nature 2015, 517, 347.

305) “Consequences of periodic α-to-β3 residue replacement for immunological recognition of peptide epitopes.” Cheloha RW, Sullivan JA, Wang T, Sand JM, Sidney J, Sette A, Cook ME, Suresh M, Gellman SH. ACS Chem. Biol. 201510, 844.

304) “Screening nylon-3 polymers, a new class of cationic amphiphiles, for siRNA delivery.” Nadithe V, Liu R, Killinger BA, Movassaghian S, Kim NH, Moszczynska AB, Master KS, Gellman SH, Merkel OM. Mol. Pharm. 201512, 362.

2014

303) “New charge-bearing amino acid residues that promote β-sheet secondary structure.” Maynard SJ, Almeida AM, Yoshimi Y, Gellman SH J. Am. Chem. Soc. 2014136, 16683.

302) “A γ-amino acid that favors 12/10-helical secondary structure in α/γ-peptides.” Giuliano MW, Maynard SJ, Almeida AM, Guo L, Guzei IA, Spencer LC, Gellman SH J. Am. Chem. Soc. 2014136, 15046.

301) “Synthetic polymers active against Clostridium difficile vegetative cell growth and spore outgrowth.” Liu R, Suárez JM, Weisblum B, Gellman SH, McBride SM J. Am. Chem. Soc. 2014136, 14498.

300) “Ternary nylon-3 copolymers as host-defense peptide mimics: beyond hydrophobic and cationic subunits.” Chakraborty S, Liu R, Hayouka Z, Chen X, Ehrhardt J, Lu Q, Burke E, Yang Y, Weisblum B, Wong GC, Masters KS, Gellman SH J. Am. Chem. Soc. 2014136, 14530.

299) “A potent α/β-peptide analogue of GLP-1 with prolonged action in vivo.” Johnson LM, Barrick S, Hager MV, McFedries A, Homan EA, Rabaglia ME, Keller MP, Attie AD, Saghatelian A, Bisello A, Gellman SH J. Am. Chem. Soc. 2014136​, 12848.

298) “Medium effects on minimum inhibitory concentrations of nylon-3 polymers against E. coli.” Choi H, Chakraborty S, Liu R, Gellman SH, Weisshaar JC PLoS One 20149, e104500.

297) “Backbone modification of a polypeptide drug alters duration of action in vivo.” Cheloha RW, Maeda A, Dean T, Gardella TJ, Gellman SH. Nat Biotechnol. 2014 ,32, 653.

296) “Hydrophobicity and Helicity Regulate the Antifungal Activity of 14-Helical β-Peptides.” Lee MR, Raman N, Gellman SH, Lynn DM, Palecek SP. ACS Chem Biol. 20149, 1613.

295) “Building Proficient Enzymes with Foldamer Prostheses.” Mayer C, Müller MM, Gellman SH, Hilvert D. Angew Chem Int Ed Engl. 2014, 53, 6978.

294) “Two interdependent mechanisms of antimicrobial activity allow for efficient killing in nylon-3-based polymeric mimics of innate immunity peptides.” Lee M, Chakraborty S, Schmidt NW, Murgai R, Gellman SH, Wong GC. Biochim Biophys Acta. 2014, 1838, 2269.

293) “Improved Glucose-Neopentyl Glycol (GNG) Amphiphiles for Membrane Protein Solubilization and Stabilization.” Cho KH, Bae HE, Das M, Gellman SH, Chae PS.Chem Asian J. 20149, 632.

292) “Mimicking the First Turn of an α-Helix with an Unnatural Backbone: Conformation-Specific IR and UV Spectroscopy of Cyclically Constrained β/γ-Peptides.” Gord JR, Walsh PS, Fisher BF, Gellman SH, Zwier TS. J Phys Chem B2014, 118, 8246.

291) “Structure–Activity Relationships among Antifungal Nylon-3 Polymers: Identification of Materials Active against Drug-Resistant Strains of Candida albicans.” Liu R, Chen X, Falk SP, Mowery BP, Karlsson AJ, Weisblum B, Palecek SP, Masters KS, Gellman SH., J Am Chem Soc. 2014136, 4333.

290) “Tuning the Biological Activity Profile of Antibacterial Polymers via Subunit Substitution Pattern.” Liu R, Chen X, Chakraborty S, Lemke JJ, Hayouka Z, Chow C, Welch RA, Weisblum B, Masters KS, Gellman SH., J Am Chem Soc. 2014136, 4410.

289) “Hydrophobic variants of ganglio-tripod amphiphiles for membrane protein manipulation”Chae PS, Cho KH, Wander MJ, Bae HE, Gellman SH, Laible PD, Biochim Biophys Acta.20141838, 278.

288) “Two-dimensional sum-frequency generation reveals structure and dynamics of a surface-bound Peptide.” Laaser JE, Skoff DR, Ho JJ, Joo Y, Serrano AL, Steinkruger JD, Gopalan P, Gellman SH, Zanni MT. J Am Chem Soc. 2014136, 956.

287) “Hydrophobic Variations of N-Oxide Amphiphiles for Membrane Protein Manipulation: Importance of Non-hydrocarbon Groups in the Hydrophobic Portion.” Chae PS, Sadaf A, Gellman SH., Chem Asian J. 20149, 110.

2013

286) “Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain.” Mortenson DE, Kreitler DF, Yun HG, Gellman SH, Forest KT. Acta Crystallogr D Biol Crystallogr2013, 2506.

285) “Evaluation of a Cyclopentane-Based γ-Amino Acid for the Ability to Promote α/γ-Peptide Secondary Structure.” Giuliano MW, Maynard SJ, Almeida AM, Reidenbach AG, Guo L, Ulrich EC, Guzei IA, Gellman SH. J Org Chem2013, 78, 12351.

284) “Improved Glucose-Neopentyl Glycol (GNG) Amphiphiles for Membrane Protein Solubilization and Stabilization.” Cho KH, Bae HE, Das M, Gellman SH, Chae PS. Chem Asian J. 2013, 9, 632.

283) “Nylon-3 Polymers That Enable Selective Culture of Endothelial Cells.” Liu R, Chen X, Gellman SH, Masters KS. J Am Chem Soc. 2013, 135, 16296.

282) “Cyclic Constraints on Conformational Flexibility in γ-Peptides: Conformation Specific IR and UV Spectroscopy.” Walsh PS, Kusaka R, Buchanan EG, James WH 3rd, Fisher BF, Gellman SH, Zwier TS. J Phys Chem A. 2013117, 12350.

281) “Novel Tripod Amphiphiles for Membrane Protein Analysis.” Chae PS, Kruse AC, Gotfryd K, Rana RR, Cho KH, Rasmussen SG, Bae HE, Chandra R, Gether U, Guan L, Kobilka BK, Loland CJ, Byrne B, Gellman SH. Chem. Eur. J. 2013, 19, 15645.

280) “Hydrophobic variants of ganglio-tripod amphiphiles for membrane protein manipulation.” Chae PS, Cho KH, Wander MJ, Bae HE, Gellman SH, Laible PD. Biochim Biophys Acta20131838, 278.

279) “Evidence for Phenylalanine Zipper-Mediated Dimerization in the X-ray Crystal Structure of a Magainin 2 Analogue” Hayouka Z, Mortenson DE, Kreitler DF, Weisblum B, Forest KT,Gellman SH, J Am Chem Soc2013, 135, 15738.

278) “Role of Ring-Constrained γ-amino Acid Residues in α/γ-peptide Folding: Single-Conformation UV and IR Spectroscopy” Kusaka R, Zhang D, Walsh PS, Gord JR, Fisher BF, Gellman SH, Zwier TS. J Phys Chem A. 2013, 117, 10847

277) “Structural Characterization of Peptide Oligomers Containing (1R,2S)-2-Aminocyclohexanecarboxylic Acid (cis-ACHC)” Choi SH, Ivancic M, Guzei IA, Gellman SH, Eur J Org Chem201317, 3464.

276) “Effects of Cyclic vs Acyclic Hydrophobic Subunits on the Chemical Structure and Biological Properties of Nylon-3 Copolymers” Chakraborty S, Liu R, Lemke JJ, Hayouka Z, Welch RA,  Weisblum B, Masters KS, Gellman SH. ACS Macro Letters20132, 753.

275) “Structure-Guided Rational Design of α/β-Peptide Foldamers with High Affinity for BCL-2 Family Prosurvival Proteins.” Smith BJ, Lee EF, Checco JW, Evangelista M, Gellman SH, Fairlie WD. Chembiochem. 201314, 1564.

274) “Interplay among Subunit Identity, Subunit Proportion, Chain Length, and Stereochemistry in the Activity Profile of Sequence-Random Peptide Mixtures.” Hayouka Z, Chakraborty S, Liu R, Boersma MD, Weisblum B, Gellman SH.J Am Chem Soc2013, 135, 11748.

273) “Differential Impact of β and γ Residue Preorganization on α/β/γ-Peptide Helix Stability in Water.” Shin YH, Mortenson DE, Satyshur KA, Forest KT, Gellman SH. J Am Chem Soc. 2013135, 8149.

272) “Nylon-3 polymers with selective antifungal activity.”, Liu R, Chen X, Hayouka Z, Chakraborty S, Falk SP, Weisblum B, Masters KS, Gellman SH. J Am Chem Soc. 2013, 135, 5270.

271) “Protein prosthesis: ß-peptides as reverse-turn surrogates.”, Arnold U, Huck BR, Gellman SH, Raines RT.,Protein Sci2013, 22, 274-9.

270) “a-Helix Mimicry with a/β-Peptides.” Johnson LM, Gellman SH. Methods Enzymol. 2013523, 407.

269)  “Carbohydrate-containing Triton X-100 analogues for membrane protein solubilization and stabilization.”, Chae PS, Wander MJ, Cho KH, Laible PD, Gellman SH. Mol Biosyst. 20139, 626.

268 ) “Glucose-Neopentyl Glycol (GNG) amphiphiles for membrane protein study” Chae PS, Rana RR, Gotfryd K, Rasmussen SG, Kruse AC, Cho KH, Capaldi S, Carlsson E, Kobilka B, Loland CJ, Gether U, Banerjee S, Byrne B, Lee JK, Gellman SH. Chem Commun (Camb)2013, 49, 2287.

2012

267) “Functionally Diverse Nylon-3 Copolymers from Readily Accessible β-Lactams.” Zhang J, Markiewicz MJ, Weisblum B, Stahl SS, Gellman SH. ACS Macro Lett. 2012, 1, 714-717.

266) “Parallel β-Sheet Vibrational Couplings Revealed by 2D IR Spectroscopy of an Isotopically Labeled Macrocycle: Quantitative Benchmark for the Interpretation of Amyloid and Protein Infrared Spectra.” Woys AM, Almeida AM, Wang L, Chiu CC, McGovern M, de Pablo JJ, Skinner JL, Gellman SH, Zanni MT. J Am Chem Soc. 2012,134, 19118-28.

265) “Strong contributions from vertical triads to helix-partner preferences in parallel coiled coils” Steinkruger JD, Bartlett GJ, Woolfson DN, Gellman SH. J Am Chem Soc. 2012134, 15652-5.

264) “Single-conformation infrared spectra of model peptides in the amide I and amide II regions: experiment-based determination of local mode frequencies and inter-mode coupling” Buchanan EG, James WH 3rd, Choi SH, Guo L, Gellman SH, Müller CW, Zwier TS.  J Chem Phys. 2012137, 094301.

263) “A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrace proteins.’ Chae PS, Rasmussen SG, Rana RR, Gotfryd K, Kruse AC, Manglik A, Cho KH, Nurva S, Gether U, Guan L, Loland CJ, Byrne B, Kobilka BK, Gellman, S.H., Chemistry201218, 9485-90.

262) “Experimental and Computational Anaylsis of Cellular interactions with nylon-3-bearing substrates.”, Liu R, Vang KZ, Kreeger PK, Gellman, S.H. Masters KS., J Biomed Mater Res A2012,100, 2750-9.

261) “New Preorganized gamma-Amino Acids as Foldmer Building Blocks.’ Guo L, Zhang W, Guzei IA, Spencer LC, Gellman, S.H., Org Lett. 2012, ASAP

260) “Extending Foldamer Design beyond α-Helix Mimicry: α/β-Peptide Inhibitors of Vascular Endothelial Growth Factor Signaling.”, Haase, H.S.; Peterson-Kaufman, K.J.; Lan Levengood, S.K.; Checco, J.W.; Murphy, W.L.; Gellman, S.H.  J Am Chem Soc. 2012,134, 7652-5.

259) “Enhancement of α-Helix Mimicry by an α/β-Peptide Foldamer via Incorporation of a Dense Ionic Side-Chain Array.”, Johnson, L.M.; Mortenson, D.E.; Yun, H.G.; Horne, W.S.; Ketas, T.J.; Lu, M. Moore, J.P.; Gellman, S.H.  J Am Chem Soc2012134, 7317-20.

258) “Polymer chain length effects on fibroblast attachment on nylon-3-modified surfaces.”, Liu, R.; Masters, K.S.; Gellman, S.H.  Biomacromolecules. 201213, 1100-5.

257) “The d’–d–d’ Vertical Triad Is Less Discriminating Than the a’–a–a’ Vertical Triad in the Antiparallel Coiled-Coil Dimer Motif.”, Steinkruger, J.D.; Bartlett, G.J.; Hadley, E.B.; Fay, L.; Woolfson, D.N.; Gellman, S.H. J Am Chem Soc2012 , 134, 2626-33.

256) “Quasiracemic crystallization as a tool to assess the accommodation of noncanonical residues in nativelike protein conformations.”, Mortenson, D.E.; Satyshur, K.A.; Guzei, I.A.; Forest, K.T.; Gellman, S.H., J Am Chem Soc. 2012, 134, 2473-2476.

255) “C-terminal functionalization of nylon-3 polymers: effects of C-terminal groups on antibacterial and hemolytic activities.”, Zhang, J.; Markiewicz, M.J.; Mowery, B.P.; Weisblum, B.; Stahl, S.S.; Gellman, S.H., Biomacromolecules. 201213, 323-331.

254) “Parallel β-sheet secondary structure is stabilized and terminated by interstrand disulfide cross-linking.”, Almeida, A.M.; Li, R.; Gellman, S.H. J Am Chem Soc. 2012134, 75-78.

253) “Evaluation of Diverse α/βBackbone Patterns for Functional α-Helix Mimicry: Analogues of the Bim BH3 Domain.”, Boersma, M.D.; Haase, H.S.; Peterson-Kaufman, K.J.; Lee, E.F.; Clarke, O.B.; Colman, P.M.; Smith, B.J.; Horne, W.S.; Fairlie, W.D.; Gellman, S.H., J Am Chem Soc. 2012, 134, 315-323.

2011

252) “Sheet-Like Assemblies of Charged Amphiphilic α/β-Peptides at the Air-Water Interface.”, Segman-Magidovich, S.; Lee, M.R.; Vaiser, V.; Struth, B.; Gellman, S.H.; Rapaport, H., Chemistry. 2011,17, 14857-14866.

251) “Evolution of Amide Stacking in Larger γ-Peptides: Triamide H-Bonded Cycles.”, Iii, W.H.; Buchanan, E.G.; Müller, C.W.; Dean, J.C.; Kosenkov, D.; Slipchenko, L.V.; Guo, L.; Reidenbach, A.G.; Gellman, S.H.; Zwier, T.S., J Phys Chem A. 2011, 115, 13783-98.

250) “Crystal structure of the β2 adrenergic receptor-Gs protein complex.”, Rasmussen, S.G.; DeVree, B.T.; Zou, Y.; Kruse, A.C.; Chung, K.Y.; Kobilka, T.S.; Thian, F.S.; Chae, P.S.; Pardon, E.; Calinski, D.; Mathiesen, J.M.; Shah, S.T.; Lyons, J.A.; Caffrey, M.; Gellman, S.H.; Steyaert, J.; Skiniotis, G.; Weis, W.I.; Sunahara, R.K.; Kobilka, B.K., Nature. 2011, 477, 549-55.

249) “Structural Basis of Bcl-x(L) Recognition by a BH3-Mimetic α/β-Peptide Generated by Sequence-Based Design.” Lee, E.F.; Smith, B.J.;Horne, W.S.; Mayer, K.N.; Evangelista, M.; Colman, P.M.; Gellman, S.H.; Fairlie, W.D., Chembiochem. 2011, 12, 2025-32.

248) “Competition between amide stacking and intramolecular H bonds in γ-peptide derivatives: controlling nearest-neighbor preferences.”, James, W.H 3rd; Buchanan, E.G.; Guo, L.; Gellman, S.H.; Zwier, T.S. J Phys Chem A. 2011, 115, 11960-70.

247) “Macrocyclic Design Strategies for Small, Stable Parallel β-Sheet Scaffolds.” Freire, F.; Gellman, S.H., J Am Chem Soc. 2011, 133, 12318.

246) “Lyotropic Liquid Crystals Formed from ACHC-Rich β-Peptides.” Pomerantz, W.C.; Yuwono, V.M.; Drake, R.; Hartgerink, J.D.; Abbott, N.L.; Gellman, S.H., J Am Chem Soc. 2011,133, 13604-13.

245) “Impact of Strand Length on the Stability of Parallel-β-Sheet Secondary Structure.” Freire, F.; Almeida, A.M.; Fisk, J.D.; Steinkruger, J.D.; Gellman, S.H., Angew Chem Int Ed Engl. 2011, 50, 8735-8.

244) “Broad distribution of energetically important contacts across an extended protein interface.”, Johnson, L.; Horne, W.S.; Gellman, S.H., J. Am. Chem. Soc., 201133,10038-41.

243) “Characteristic Structural Parameters for the γ-Peptide 14-Helix: Importance of Subunit Preorganization.”, Guo, L.;  Zhang, W.; Reidenbach, A.G.; Giuliano, M.W.; Guzei, I.A.; Spencer, L.C.; Gellman, S.H., Angew. Chem. Int. Ed Engl., 2011, 50,5843-6.

242) “Structural mimicry of the α-Helix in aqueous solution with an isoatomic α/β/γ-peptide backbone.”, Sawada, T.; Gellman, S. H., J. Am. Chem. Soc., 2011,133, 7336-7339.

241) “Identification of chromatophore membrane protein complexes formed under different nitrogen availability conditions in Rhodospirillum rubrum”, Selao, T. T.; Branca, R.; Chae, P. S.; Lehti, J.; Gellman, S. H.; Rasmussen, S.G.F.; Nordlund, S.; Nor, A., J. Proteome Res.2011,10, 2703-2714.

240) “Single-molecule force spectroscopy of β- peptides that display well-defined three-dimensional chemical patterns.”, Acevedo-Velz, C.; Andre, G.; Dufrene, Y.F.; Gellman, S.H.; Abbott, N.L., J. Am. Chem. Soc., 2011133, 3981-3988.

239) “Structure and function of an irreversible agonist-β2 adrenoceptor complex”,Rosenbaum, D. M.;Zhang, C.; Lyons, J. A.; Holl, R.; Aragao, D.; Arlow, D. H.; Rasmussen, S. G.; Choi, H. J.; Devree, B. T.; Sunahara, R. K.; Chae, P. S.; Gellman, S. H.; Dror, R. O.; Shaw, D. E.; Weis, W. I.; Caffrey, M.; Gmeiner, P.; Kobilka, B. K., Nature2011469, 236-240.

238) “Structure of a nanobody-stabilized active state of the beta(2) adrenoceptor”,Rasmussen, S. G.;Choi,H. J.;Fung,J. J.;Pardon,E.;Casarosa,P.;Chae,P. S.;Devree,B. T.;Rosenbaum,D. M.;Thian,F. S.;Kobilka,T. S.;Schnapp,A.;Konetzki,I.;Sunahara,R. K.;Gellman,S. H.; Pautsch,A.; Steyaert,J.; Weis, W. I. and Kobilka, B. K. , Nature, 2011, 469, 175-180.

237) “Lyotropic liquid crystalline phases from helical β-peptides as alignment media”,Thiele, C. M.;Pomerantz,W. C.;Abbott,N. L. and Gellman,S. H. ,Chem.Commun.(Camb), 2011, 47, 502-504.

2010

236) “Tandem facial amphiphiles for membrane protein stabilization”,Chae, P. S.;Gotfryd,K.;Pacyna,J.;Miercke,L. J.;Rasmussen,S. G.;Robbins,R. A.;Rana,R. R.;Loland,C. J.;Kobilka,B.;Stroud,R.;Byrne,B.;Gether,U. and Gellman,S. H. ,J.Am.Chem.Soc.,2010,132,16750-16752.

235) “Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins”,Chae, P. S.;Rasmussen,S. G.;Rana,R. R.;Gotfryd,K.;Chandra,R.;Goren,M. A.;Kruse,A. C.;Nurva,S.;Loland,C. J.;Pierre,Y.;Drew,D.;Popot,J. L.;Picot,D.;Fox,B. G.;Guan,L.;Gether,U.;Byrne,B.;Kobilka,B. and Gellman,S. H. ,Nat.Methods,2010,7,1003-1008.

234) “Crystallographic characterization of 12-helical secondary structure in beta-peptides containing side chain groups”,Choi, S. H.;Guzei,I. A.;Spencer,L. C. and Gellman,S. H. ,J.Am.Chem.Soc.,2010,132,13879-13885.

233) “Structural consequences of beta-amino acid preorganization in a self-assembling alpha/beta-peptide: Fundamental studies of foldameric helix bundles”,Price, J. L.;Horne,W. S. and Gellman,S. H. ,J.Am.Chem.Soc.,2010,132,12378-12387.

232) “Polyelectrolyte multilayers fabricated from antifungal beta-peptides: Design of surfaces that exhibit antifungal activity against candida albicans”,Karlsson, A. J.;Flessner,R. M.;Gellman,S. H.;Lynn,D. M. and Palecek,S. P. ,Biomacromolecules,2010,11,2321-2328.

231) “Kinetics of anionic ring-opening polymerization of variously substituted beta-Lactams: homopolymerization and copolymerization”,    Zhang, J.; Gellman, S.H.; Stahl, S.S.,Macromolecules,2010,  43,  5618-5626.

230) “Helix formation in preorganized beta/gamma-peptide foldamers: Hydrogen-bond analogy to the alpha-helix without alpha-amino acid residues”,Guo, L.;Almeida,A. M.;Zhang,W.;Reidenbach,A. G.;Choi,S. H.;Guzei,I. A. and Gellman,S. H. ,J.Am.Chem.Soc.,2010,132,7868-7869.

229) “Biophysical mimicry of lung surfactant protein B by random nylon-3 copolymers”,Dohm, M. T.;Mowery,B. P.;Czyzewski,A. M.;Stahl,S. S.;Gellman,S. H. and Barron,A. E. ,J.Am.Chem.Soc.,2010,132,7957-7967.

228) “Side-chain pairing preferences in the parallel coiled-coil dimer motif: Insight on ion pairing between core and flanking sites”,Steinkruger, J. D.;Woolfson,D. N. and Gellman,S. H. ,J.Am.Chem.Soc.,2010,132,7586-7588.

227) “Crystallographic characterization of N-oxide tripod amphiphiles”,Chae, P. S.;Guzei,I. A. and Gellman,S. H. ,J.Am.Chem.Soc.,2010,132,1953-1959.

226) “Highly stable pleated-sheet secondary structure in assemblies of amphiphilic alpha/beta-peptides at the air-water interface”,Segman, S.;Lee,M. R.;Vaiser,V.;Gellman,S. H. and Rapaport,H. ,Angew.Chem.Int.Ed Engl.,2010,49,716-719.

225) “Detection and analysis of chimeric tertiary structures by backbone thioester exchange: Packing of an alpha helix against an alpha/beta-peptide helix”,Price, J. L.;Hadley,E. B.;Steinkruger,J. D. and Gellman,S. H. ,Angew.Chem.Int.Ed Engl.,2010,49,368-371.

224) “Laser spectroscopy of conformationally constrained alpha/beta-peptides: Ac-ACPC-phe-NHMe and ac-phe-ACPC-NHMe”,James, W. H.,3rd;Baquero,E. E.;Choi,S. H.;Gellman,S. H. and Zwier,T. S. ,J Phys Chem A,2010,114,1581-1591.

223) “Tripod Amphiphiles for Membrane Protein Manipulation,” Chae, P. S. :Laible, P. D.  and Gellman,S. H.,  Mol. BioSystems 20106, 89.

2009

222) “Nylon-3 Co-Polymers that Generate Cell-Adhesive Surfaces Identified by Library Screening,” M.-r. Lee, S. S. Stahl, S. H. Gellman and K. S. Masters J. A m. Chem. Soc. 2009, 131, 16779.

221) “Stereospecific Synthesis of Conformationally Constrained γ-Amino Acids:  New Foldamer Building Blocks that Support Helical Secondary Structure,” L. Guo, Y. Chi, A. Almeida, I. A. Guzei, B. Parker and S. H. Gellman J. Am. Chem. Soc. 2009, 131, 16018.

220) “Intramolecular Amide Stacking and its Competition with Hydrogen Bonding in a Small Foldamer,” W. H. James, C. W. Müller, E. G. Buchanan, M. G. D. Nix, L. Guo, L. Roskop, M. S. Gordon, L. V. Slipchenko, S. H. Gellman and T. W. Zwier J. Am. Chem. Soc.  2009, 131, 14243.

219) “Structural and Biological Mimicry of Protein Surface Recognition by α/β-Peptide Foldamers,” W. S. Horne, L. M. Johnson, T. J. Ketas, P. J. Klass e, M. Lu, J. P. Moore and S. H. Gellman Proc. Natl. Acad. Sci. USA 2009, 106, 14751.

218) “In Situ Monitoring of Backbone Thioester Exchange by 19F NMR,” W. C. Pomerantz, E. B.  Hadley, C. G. Fry and S. H. Gellman ChemBioChem 2009, 10, 2177.

217) “An α/β-Peptide Helix Bundle with a Pure β3-Amino Acid Core and a Distinctive Quaternary Str ucture,” M. A. Guiliano, W. S. Horne and S. H. Gellman J. Am. Chem. Soc. 2009, 131, 9860.

216) “Peptide Inhibitors Identify Roles for SSB C-Terminal Residues in SSB/Exonuclease I Complex Formation,” D. Lu, M. A. Windsor, S. H. Gellman and J. L. Keck Biochemistry 2009, 48, 6764.

215) “Effect of Sequence and Structural Properties on 14-Helical β-Peptide Activity Against Candida albicans Planktonic Cells and Biofilms,” A. J. Kar lsson, W. C. Pomerantz, K. J. Neilsen, S.  H. Gellman and S. P. Palecek ACS Chem. Biol. 2009, 4, 567.

214) “Catalytic Transamidation Reactions Compatible with Tertiary Amide Metathesis under Ambient Conditions,” N. A. Stephenson, J. Zhu, S. H. Gellman and S. S. Stahl J. Am. Chem. Soc. 2009, 131, 10003.

213) “Structure-Activity Relationships Among Random Nylon-3 Copolymers that Mimic Antibacterial Host-Defense Peptides,” B. M. Mowery, A. M. Lindner,  B. Weisblum, S. S. Stahl and S. H. Gellman J. Am. Chem. Soc. 2009, 131, 9735.

212) “Macrocyclic Design Strategies for Small, Stable Parallel β-Sheet Scaffolds,” F. Friere and S. H. Gellman J. Am. Chem. Soc. 2009, 131, 7970.

211) “Single-Conformation and Diastereomer Specific Ultraviolet and Infrared Spectroscopy of Model Synthetic Foldamers:  α/β-peptides,”  W. James, E. Baquero, V. Shubert, S. H. Choi, S. H. Gellman and T. Zwier  J. Am. Chem. Soc. 2009, 131, 6574.

210) “High-Resolution Structural Characterization of a Helical α/β-Peptide Foldamer Bound to the Anti-Apoptotic Protein  Bcl-xL,” E. F. Lee, J. D. Sadowsky, B. J. Smith, P. E. Czabotar, K. J. Peterson-Kaufman, P. M. Colman, S. H. Gellman and W. D. Fairlie Angew. Chem. Int. Ed. 2009, 48, 4318.

209) “Crystallographic Characterization of Helical Secondary Structures in 2:1 and 1:2 α/β-Peptides,”  S. H. Choi, I. Guzei, L. Spencer and S. H. Gell man J. Am. Chem. Soc. 2009, 131, 2917.

208) “Access to Poly-β-Peptides with Functionalized Side Chains and End Groups via Controlled Ring-Opening Polymerization of β -Lactams,” J. Zhang, D. Kissounko, S. Lee, S. H. Gellman and S. S. Stahl J. Am. Chem. Soc. 2009, 131, 1589.

207) “A Rationally Designed Aldolase Foldamer,” M. M. Müller, M. A. Windsor, W. C. Pomerantz, S. H. Gellman and D. Hilvert Angew. Chem. Int. Ed. 2009, 48, 922.

2008

206) “Synthesis of β-Lactams Bearing Functionalized Side Chains from a Readily Available Precursor,” M.-r. Lee, S. S. Stahl and S. H. Gellman Org. Lett. 2008, 10, 5317.

205) “Mechanical Stability of Helical β-Peptides and a Comparison of Explicit and Implicit Solvent Models,” C. A. Miller, S. H. Gellman, N. L. Abbott, J. J. de Pablo Biophys. J. 2008, 95, 3123.

204) “Characterization of Nanofibers Formed by Self-Assembly of β-Peptide Oligomers Using Small Angle X-Ray Scattering,” C. L. Pizzery, W. C. Pomerant z, B.-J. Sung, V. M. Yuwono, J. D. Hartgerink, S. H. Gellman, A. Yethiraj and N. L. Abbott J. Chem. Phys. 2008, 129, 095103.

203) “Foldamers with Heterogeneous Backbones,” W. S. Horne and S. H. Gellman Acc. Chem. Res. 2008, 41, 1399.

202) “Comparison of Design Strategies for Promotion of β-Peptide 14-Helix Stability in Water,” E. Vaz, W. C. Pomerantz,  M. Geyer, S. H. Gellman and L . Brunsveld ChemBioChem 2008, 9, 2254.

201) “Glycotripod Amphiphiles for Solubilization and Stabilization of a Membrane Protein Superassembly:  Importance of Branching in the Hydrophilic Portion,” P. S. Chae, M. J. Wan der, A. P. Bowling, P. D. Laible and S. H. Gellman ChemBioChem 2008 9, 1706.

200) “Interplay Among Side Chain Sequence, Backbone Composition and Residue Rigidification in Polypeptide Folding and Assembly,” W. S.  Horne, J. L. Price and S. H. Gellman Proc. Natl. Acad. Sci. USA 2008, 105, 9151.

199) “Dipole-Induced Self-Assembly of Helical β-Peptides,” C. A. Miller, J. P. Hernández-Ortiz, N. L. Abbott, S. H. Gellman and J. J. de Pablo J. Chem. Phys. 2008, 129, 015102.

198) “Diacid Linkers that Promote Parallel β-Sheet Secondary Structure in Water,” F. Friere, J. D. Fisk, A. J. Peoples, M. Invancic, I. A. Guzei and S . H. Gellman J. Am. Chem. Soc. 2008, 130, 7839.

197) “Hydrophile-Scanning as a Complement to Alanine-Scanning for Exploring and Manipulating Protein-Protein Recognition:  Application to the Bim BH3 Domain,” M. D. Boersma, J. D. Sadowsky, Y. Tomita and S. H. Gellman Protein Sci. 2008, 17, 1232.

196) “Inhibition of Herpes Simplex Virus Type 1 Infection by Cationic β-Peptides,” R. Akkarawongsa, T. B. Potocky, E. English, S. H. Gellman and C. R. Brandt Antimicrob. Agents Chemother. 2008, 52, 2120.

195) “Dual Mechanism of Bacterial Lethality for a Cationic Sequence-Random Copolymer that Mimics Host-Defense Antimicrobial Peptides,” R. F. Epand, B. P. Mowery, S. E. Lee, S. S. Stahl, R. I. Lehrer, S. H. Gellman and R. M. Epand J. Mol. Biol. 2008, 379, 38.

194) “A Fluorescence Polarization Assay for Identifying Ligands that Bind to Vascular Endothelial Growth Factor,” K. J. Peterson, J. D. Sadowsky, E. A. Scheef, S. Pal, K. D. Koure ntzi, R. C. Willson, E. H. Bresnick, N. Sheibani and S. H. Gellman Anal. Biochem. 2008, 378, 8.

193) “Distinctive Circular Dichroism Signature for 14-Helix-Bundle Formation by β-Peptides,” W. C. Pomerantz, T. L. R. Grygiel, J. R. Lai and S. H. Ge llman Org. Lett. 2008, 10, 1799.

192) “Crystallographic Characterization of Helical Secondary Structures in α/β-Peptides with 1:1 Residue Alternation,” S. H. Choi, I. Guzei, L. Spence r and S. H. Gellman J. Am. Chem. Soc. 2008, 130, 6544.

191) “Enantioselective Organocatalytic Michael Addition of Aldehydes to Nitroethylene:  Efficient Access to γ2-Amino Acids,&qu ot; Y. Chi, L. Guo, N. Kopf and S. H. Gellman  J. Am. Chem. Soc.  2008, 130, 5608.

190) “Establishing Effective Simulation Protocols for β- and α/β-Peptides. II. Molecular Mechanical (MM) Model for a Cyclic β-Residue,” X. Zhu, P. Koenig, S. H. Gellman, A. Yethiraj,  C. Qiang J. Phys. Chem. B 2008, 112, 5439.

189) “Single-Conformation Ultraviolet and Infrared Spectroscopy of Model Synthetic Foldamers:  β-Peptides Ac-β3-hPhe-β3-hAla-NHMe and Ac-β3-hAla-β3-hPhe-NHMe,& quot; E. E. Baquero, W. H. James III, S. H. Choi, S. H. Gellman and T. S. Zwier  J. Am. Chem. Soc. 2008, 130, 4795.

188) “Single-Conformation Ultraviolet and Infrared Spectroscopy of Model Synthetic Foldamers:  β-Peptides Ac-β3-hPhe-NHMe and Ac-β3-hTyr-NHMe,” E. E. Baquero, W. H. James III, S. H. Choi, S. H. Gellman and T. S. Zwier  J. Am. Chem. Soc. 2008, 130, 4784.

187) “Sequence-Based Design of α/β-Peptide Foldamers that Mimic α-Helical BH3 Domains,” W. S. Horne, M. D. Boersman, M. A . Windsor and S. H. Gellman Angew. Chem. Int. Ed. 2008, 47, 2853.

186) “Exploration of Structure/Activity Relationships among Foldamer Ligands for a Specific Protein Binding Site via Parallel and Split-and-Mix Library Synthesis,” J. K. Murray, J . D. Sadowsky, M. Scalf, L. M. Smith, Y. Tomita and S. H. Gellman J. Combi. Chem. 2008, 10, 204.

185) “Nanofibers and Lyotropic Liquid Crystals from a New Class of Self-Assembling β-Peptides,” W. C. Pomerantz, V. M. Yuwono, C. L. Pizzey, J. D. Har tgerink, N. L. Abbott and S. H. Gellman Angew. Chem. Int. Ed. 2008, 47, 1241.

184) “Preferred Side-chain Constellations at Antiparallel Coiled-coil Interfaces,” E. B. Hadley, O. D. Testa, D. N. Woolfson and S. H. Gellman Proc. Natl. Ac ad. Sci. USA 2008, 105, 530.

183) “Discovery and Mechanistic Study of AlIII-Catalyzed Transamidation of Tertiary Amides,” J. M. Hoerter, K. M. Otte, S. H. Gellman, Q. Cui and S. S . Stahl J. Am. Chem. Soc. 2008, 130, 647.

2007

182) “Mimicry of Antimicrobial Host-Defense Peptides by Random Co-Polymers,” B. P. Mowery, S. E. Lee, D. A. Kissounko, R. F. Epand, R. M. Epand, B. Weisblum, S. S. Stahl and S. H. Gellman J. Am. Chem. Soc. 2007, 129, 15474.

181) “Crystallographic Characterization of the α/β-Peptide 14/15-Helix,” S. H. Choi, I. A. Guzei and S. H. Gellman J. Am. Chem. Soc. 2007, 129, 13780.

180) “Thermodynamic Analysis of β-Sheet Secondary Structure Via Backbone Thioester Exchange,” E. B. Hadley, A. M. Witek, F. Friere, A. J. Peoples and S. H. Gellman Angew. Chem. Int. Ed. 2007, 46, 7056.

179) “Targeting Protein-Protein Interactions:  Lessons from p53/MDM2,” J. K. Murray and S. H. Gellman, Biopol. – Pept.  Sci. 200 7, 88, 657.

178) “Sequence Dependent Behavior of Amphiphilic β-Peptides on Gold Surfaces,” W. C. Pomerantz, K. D. Cadwell, Y.-J. Hsu, S. H. Gellman and N. L. Abbo tt  Chem. Materials 2007, 19, 4436.

177) “H/D Exchange- and Mass Spectrometry-Based Strategy for the Thermodynamic Analysis of Protein-Ligand Binding,” L. Tang, E. D. Hopper, Y. Tong, J. D. Sadowsky, K. J. Peterson, S. H. Gellman and M. C. Fitzgerald Anal. Chem. 2007, 79, 5869.

176) “Discrete Heterogeneous Quaternary Structure Formed by α/β-Peptide Foldamers and α-Peptides,” J. L. Price, W. S. Hor ne and S. H. Gellman J. Am. Chem. Soc. 2007, 129, 6376.

175) “HeLa Cell Entry by Guanidinium-Rich β-Peptides:  Importance of Specific Cation-Cell Surface Interactions,” T. B. Potocky, J. Silvius, A. K. Meno n and S. H. Gellman ChemBioChem 2007, 8, 917.

174) “Exploration of Backbone Space in Foldamers Containing α- and β-Amino acid Residues: Application to Developing Protease-R esistant Oligomers that Bind Tightly to the BH3-Recognition Cleft of Bcl-xL,” J. D. Sadowsky, J. K. Murray, Y. Tomita and S. H. Gellman ChemBioChem 200 7, 8, 903.

173) “Practical Synthesis of Enantiomerically Pure β2-Amino Acids via Proline-Catalyzed Diastereoselective Aminomethylation of Aldehydes,” Y. Chi, E. P. English, W. C. Pomerantz, W. S. Horne, L. A. Joyce, L. R. Alexander, W. S. Fleming, E. A. Hopkins and S. H. Gellman J. Am. Chem. Soc. 2007, 129, 6050.

172) “Origins of the High 14-Helix Propensity of Cycohexyl-Rigidified Residues in β-Peptides,” M. Lee, T. L. Raguse, M. Schinnerl, W. C. Pomerantz, X. Wang, P. Wipf and S. H. Gellman Org. Lett. 2007, 9, 1801.

171) “Helix-Bundle Quaternary Structure from α/β-Peptide Foldamers,” W. S. Horne, J. L. Price, J. L. Keck and S. H. Gellman J. A m. Chem. Soc. 2007, 129, 4178.

170) “Parallel Synthesis of Peptide Libraries Using Microwave Irradiation,” J. K. Murray and S. H. Gellman, Nat.  Protocols 2007 , 2, 624.

169) “TiIV-Mediated Reactions between Primary Amines and Secondary Carboxamides: Amidine Formation Versus Transamidation,” D. A. Kissounko, J. M. Hoer ter, I. A. Guzei, Q. Cui, S. H. Gellman and S. S. Stahl J. Am. Chem. Soc. 2007, 129, 1776.

168) “Catalytic Metathesis of Simple Secondary Amides,” C. M. Bell, D. A. Kissounko, S. H. Gellman and S. S. Stahl Angew. Chem. Int. Ed. 2007, 46, 761.

167) “Interplay Among Folding, Sequence, and Lipophilicity in the Antibacterial and Hemolytic Activities of α/β-Peptides,” M. A. Schmitt, B. Weisblum and S. H. Gellman J. Am. Chem. Soc. 2007, 129, 417.

166) “(α/β +α)-Peptide Antagonists of BH3 Domain/Bcl-xL Recognition:  Toward General Strategies f or Foldamer-Based Inhibition of Protein-Protein Interactions,” J. D. Sadowsky, W. D. Fairlie, E. B. Hadley, H.-S. Lee, N. Umezawa, Z. Nikolovska-Coleska, S. Wang, D. C. S. Huang, Y. Tomita and S. H. Gellman  J . Am. Chem. Soc. 2007, 129, 139.

165)  “Solution Structure of a Small Protein Containing a Fluorinated Side Chain in the Core,” G. Cornilescu, E. B. Hadley, M. G. Woll, J. L. Markley, S. H. Gellman and C. C. Corn ilescu Protein Sci. 2007, 16, 14.

2006

164) “An Antiparallel α-Helical Coiled-Coil Model System for Rapid Assessment of Side Chain Recognition at the Hydrophobic Interface,” E. B. Hadley an d S. H. Gellman J. Am. Chem. Soc. 2006, 128, 16444.

163) “Roles of Salt and Conformation in the Biological and Physicochemical Behavior of Protegrin-1 and Designed Analogues:  Correlation of Antimicrobial, Hemolytic and Lipid Bilayer-Pe rturbing Activities,” J. R. Lai, R. F. Epand, B. Weisblum, R. M.  Epand and S. H. Gellman Biochemistry 2006, 45, 15718.

162) “Stabilizing and Destabilizing Effects of Phenylalanine to F5-Phenylalanine Mutations on the Folding of a Small Protein,” M. G. Woll, E. B. Hadle y, S. Mecozzi and S. H. Gellman J. Am. Chem. Soc. 2006, 128, 15932.

161) “An Antiangiogenic Neurokinin-B/Thromboxane A2 Regulatory Axis,” S. Pal, J. Wu, J. K. Murray, S. H. Gellman, M. A. Wozniak, P. J. Keely, M. E. Boyer, T. M. Gomez, S. M. Hasso , J. F. Fallon and E. H. Bresnick J. Cell Biol. 2006, 174, 1047.

160) “Thermodynamic Stability of β-Peptide Helices and the Role of Cyclic Residues,” N. Rathore, S. H. Gellman and J. J. de Pablo Biophys. J. 2006, 91, 3425.

159) “Antifungal Activity from 14-Helical β-Peptides,” A. J. Karlsson, W. C. Pomerantz, B. Weisblum, S. H. Gellman and S. P. Palecek J. Am. Chem. Soc. 2006, 128, 12630.

158) “Role of Membrane Lipids in the Mechanism of Bacterial Species Selective Toxicity by Two Antimicrobial α/β-Peptides,” R. Epand, M. A. Schmitt, S. H. Gellman and R. Epand Biochim. Biophys. Acta 2006, 1758, 1343.

157) “Lyotropic Liquid Crystals from Designed Helical β-Peptides,” W. C. Pomerantz, N. L. Abbott and S. H. Gellman J. Am. Chem. Soc. 2006, 128, 8730.

156) “Thermodynamic Analysis of Autonomous Parallel β-Sheet Formation in Water,” J. D. Fisk, M. A. Schmitt and S. H. Gellman J. Am. Chem. Soc. 2006, 128, 7148.

155) “Enantioselective Organocatalytic Aminomethylation of Aldehydes:  A Role for Ionic Interactions and Efficient Access to β2-Amino Acids,” Y. Chi and S. H. Gellman J. Am. Chem. Soc. 2006, 128, 6804.

154) “Mechanism of AlIII-Catalyzed Transamidation of Unactivated Secondary Carboxamides,” J. M. Hoerter, K. M. Otte, S. H. Gellman and S. S. Stahl J. Am. Chem. Soc. 2006, 128, 5177.

153) “New Helical Foldamers:  Heterogeneous Backbones with 1:2 and 2:1 α:β-Amino Acid Residue Patterns,” M. A. Schmitt, S.-H. Choi, I. A. Guzei and S. H. Gellman J. Am. Chem. Soc. 2006, 128, 4538.

152) “Rational Development of β-Peptide Inhibitors of Human Cytomegalovirus Entry,” E. P. English, R. S. Chumanov, S. H. Gellman and T. Compton J. Biol. Chem. 2006, 281, 2661.

151) “Microwave-Assisted Parallel Synthesis of a 14-Helical β-Peptide Library,” J. K. Murray and S. H. Gellman J. Comb. Chem. 2006, 8, 58.

2005

150) “Bacterial Species Selective Toxicity of Two Isomeric α/β-Peptides:  Role of Membrane Lipids,” R. F. Epand, M. A. Schmitt, S. H. Gellman, A. Sen, M. Auger, D. W. Hughes and R. M. Epand Mol. Membr. Biol. 2005, 22, 457.

149) “Titanium(IV)-Mediated Conversion of Carboxamides to Amidines and Implications for Catalytic Transamidation,” D. A. Kissounko, I. A. Guzei, S. H. Gellman and S. S. Stahl Organometallics 2005, 24, 5208.

148) “Efficient Synthesis of a β-Peptide Combinatorial Library with Microwave Irradiation,” J. K. Murray, B. Farooqi, J. D. Sadowsky, M. Scalf, W. A. Freund, L. M. Smith, J. Chen and S. H. Gellman J. Am. Chem. Soc. 2005, 127, 13271.

147) “Residue Requirements for Helical Folding in Short α/β-Peptides: Crystallographic Characterization of the 11-Helix in an Optimized Sequence,” M. A. Schmitt, S. H. Choi, I. A. Guzei and S. H. Gellman J. Am. Chem. Soc. 2005, 127, 13130.

146) “Diphenylprolinol Methyl Ether:  A Highly Enantioselective Catalyst for Michael Addition of Aldehydes to Enones,” Y. Chi and S. H. Gellman Org. Lett. 2005, 7, 4253.

145) “Chimeric (α/β +α)-Peptide Ligands for the BH3-Recognition Cleft of Bcl-xL: Critical Role of the Molecular Scaffold in Protein Surface Recognition,” J. D. Sadowsky, M. A. Schmitt, H.-S. Lee, N. Umezawa, S. Wang, Y. Tomita and S. H. Gellman J. Am. Chem. Soc. 2005, < span class=”style_1″>127, 11966.

144) “Enantioselective Organocatalytic Michael Additions of Aldehydes to Enones with Imidazolidinones: Co-Catalyst Effects and Evidence for an Enamine Intermediate,” T. J. Peelen, Y. R. Chi and S. H. Gellman J. Am. Chem. Soc. 2005, 127, 11598.

143)  “Use of Parallel Synthesis to Probe Structure-Activity Relationships among 12-Helical β-Peptides: Evidence of a Lower Limit on Antimicrobial Activity ,” E. A. Porter, B. Weisblum and S. H. Gellman J. Am. Chem. Soc. 2005, 127, 11516.

142) “Crystallization of Bacteriorhodopsin Solubilized by a Tripod Amphiphile,” M. J. Theisen, T. B. Potocky, D. T. McQuade, S. H. Gellman and M. L. Chiu  Bi ochim. Biophys. Acta – Proteins and Proteomics 2005, 1751, 213.

141) “A Rapid 1H NMR Assay for Enantiomeric Excess of α-Substituted Aldehydes,” Y. R. Chi, T. J. Peelen and S. H. Gellman Org. Lett. 2005, 7, 3469.

140) “Effects of Side Chain Configuration and Backbone Spacing on the Gene Delivery Properties of Lysine-Derived Cationic Polymers,”  S. E. Eldred, M. R. Pancost, K. M. Otte, D. R ozema, S. S. Stahl and S. H. Gellman Bioconj. Chem. 2005, 16, 694.

139) “Synthesis of 2,2-Disubstituted Pyrrolidine-4-Carboxylic Acid Derivatives and Their Incorporation into β-Peptide Oligomers,” B. R. Huck and S. H. Gellman J. Org. Chem. 2005, 70, 3353.

138) “An Autonomously Folding β-Hairpin Derived from the Human YAP65 WW Domain:  Attempts to Define a Minimum Ligand-Binding Motif,” J. F. Espinsoa, F . A. Syud and S. H. Gellman, Biopol. – Pept. Sci. 2005, 80, 303.  (Memorial issue for Murray Goodman)

137) “Application of Microwave Irradiation to the Synthesis of 14-Helical β-Peptides,” J. K. Murray and S. H. Gellman Org. Lett< /span>. 2005, 7, 1517.

136) “Effects of Conformational Stability and Geometry of Guanidinium Display on Cell Entry by β-Peptides,” T. B. Potocky, A. K. Menon and S. H. Gellm an J. Am. Chem. Soc. 2005, 127, 3686.

2004

135) “Synthesis of 4,4-Disubstituted 2-Aminocyclopentanecarboxylic Acid Derivatives and Their Incorporation into 12-Helical β-Peptides,” T. J. Peelen, Y. R. Chi, E. P. English and S. H. Gellman Org. Lett. 2004, 6, 4411.

134) “Backbone Thioester Exchange:  A New Approach to Evaluating Higher Order Structural Stability in Polypeptides,” M. G. Woll and S. H. Gellman J. Am. Chem . Soc. 2004, 126, 11172.

133) “Hydrophobic Core Repacking in a Coiled-Coil Dimer via Phage Display:  Insights into Plasticity and Specificity at a Protein-Protein Interface,” J. R. Lai, J. D. Fisk, B. Wei sblum and S. H. Gellman J. Am. Chem. Soc. 2004, 126, 10514.

132) “Antimicrobial 14-Helical β-Peptides:  Potent Bilayer Disrupting Agents,” R. F. Epand, T. L. Raguse, S. H. Gellman and R. M. Epand Biochemistry 2004, 43, 9527.

131) “Unexpected Relationships Between Structure and Function in α/β-Peptides:  Antimicrobial Foldamers with Heterogeneous Backbones,” M. A. Schmitt, B. Weisblum and S. H. Gellman J. Am. Chem. Soc. 2004, 126, 6848.

130) “Effects of Alternative Side Chain Pairings and Reverse Turn Sequences on Antiparallel Sheet Structure in β-Peptide Hairpins,” J. M. Langenhan an d S. H. Gellman Org. Lett. 2004, 6, 937.

129) “Biocidal Activity of Polystyrenes that are cationic by Virtue of Protonation,” M. A. Gelman, D. M. Lynn, B. Weisblum and S. H. Gellman Org. Lett. 2004, 6, 557.

128) “Two Helical Conformations from a Single Foldamer Backbone:  Split Personality in Short α/β-Peptides,” A. Hayen, M. A. Schmitt, F. Ngassa, K. A. Thomasson and S. H. Gellman Angew. Chem. Int. Ed. 2004, 43, 505.

2003

127) “Cytoplasmic and Nuclear Delivery of a TAT-Derived Peptide and a β-Peptide after Endocytic Uptake into HeLa Cells,” T. B. Potocky, A. K. Menon an d S. H. Gellman J. Biol. Chem. 2003, 278, 50188.

126) “Selective Binding of TAR RNA by a Tat-Derived β-Peptide,” M. A. Gelman, S. Richter, H. Cao, N. Umezawa,  S. H. Gellman and T. M. Rana Org. Lett. 2003, 5, 3563.

125) “Molecular Architecture with Functionalized β-Peptide Helices,” A. M. Brückner, P. Chakraborty, S. H. Gellman and U. Diederichsen Angew. Chem. Int. Ed. 2003, 42, 4395.

124) “Synthesis of Novel Nucleo-β-Amino Acids and Nucleobase-Functionalized β-Peptides,” A. M. Brückner, M. Garcia, A. Ma rsh, S. H. Gellman and U. Diederichsen Eur. J. Org. Chem. 2003, 3555.

123) “Preparation of Protected Syn-α,β-Disubstituted β-Amino Acids t hat Contain Polar Side Chain Functionality,” J. M. Langenhan and S. H. Gellman, J. Org. Chem. 2003, 68, 6440.

122) “Secondary Structural Preferences of 2,2-Disubstituted Pyrrolidine-4-Carboxylic Acid Oligomers: β-Peptide Foldamers that Cannot Form Internal Hydrogen Bonds,” B. R. Huck, J. D. Fisk, I. D. Guzei, H. A. Carlson and S. H. Gellman J. Am. Chem. Soc. 2003, 125, 9035.

121) “Accommodation of α-Substituted Residues in the β-Peptide 12-Helix:  Expanding the Range of Substitution Patterns Availab le to a Foldamer Scaffold,” J.-S. Park, H.-S. Lee, J. R. Lai, B. M. Kim and S. H. Gellman J. Am. Chem. Soc. 2003, 125, 8539.

120) “Parallel Sheet Secondary Structure in β-Peptides,” J. M. Langenhan, I. A. Guzei and S. H. Gellman Angew. Chem. Int. Ed. 2003, 42, 2402.

119) “Environment-Independent 14-Helix Formation in Short β-Peptides:  Striking a Balance Between Shape Control and Functional Diversity,” T. L. Ragus e, J. R. Lai and S. H. Gellman J. Am. Chem. Soc. 2003, 125, 5592.

118) “Catalytic Transamidation under Moderate Conditions,” S. E. Eldred, D. A. Stone, S. H. Gellman and S. S. Stahl J. Am. Chem. Soc. 2003, 125, 3422.

117) “Interactions of the Antimicrobial β-Peptide β-17 with Phospholipid Vesicles Differ from Membrane Interactions of Magaini ns,” R. F. Epand, N. Umezawa, E. A. Porter, S. H. Gellman and R. M. Epand Eur. J. Biochem. 2003, 270, 1240.

116) “Reinvestigation of the Proposed Folding and Self-Association of the Neuropeptide Head Activator,” J. R. Lai and S. H. Gellman, Protein Sci. 2003, 12, 560.

115) “Efficient Synthesis of Enantiomerically Pure β2-Amino Acids via Chiral Oxazolidinones,” H.-S. Lee, J.-S. Park, B. M . Kim and S. H. Gellman J. Org. Chem. 2003, 68, 1575.

114) “Influence of Strand Number on Antiparallel β-Sheet Stability in Designed Three- and Four-Stranded β-Sheets,” F. A. Syud, H. E. Stanger, H. S. Mortell, J. F. Espinosa, J. D. Fisk, C. G. Fry and S. H. Gellman, J. Mol. Biol. 2003, 326, 553.

113) “Asymmetric Synthesis of a New Helix-Forming β-Amino Acid:  Trans-4-Aminopiperidine-3-Carboxylic Acid,” M. Schinnerl , J. Murray, J. M. Langenhan and S. H. Gellman Eur. J. Org. Chem. 2003, 721.

2002

112) “Evidence that the β-Peptide 14-Helix is Stabilized by β3-Residues with Sidechain Branching Adjacent to the β-Carbon,” T. R. Raguse, J. R. Lai and S. H. Gellman, Helv. Chim. Acta 2002, 85, 4154 (issue in honor of the 65th birthday of D. Seebach).

111) “Structure-Activity Studies of 14-Helical Antimicrobial β-Peptides:  Probing the Relationship Between Conformational Stability and Antimicrobial Poten cy,” T. R. Raguse, E. A. Porter, B. Weisblum and S. H. Gellman J. Am. Chem. Soc. 2002, 124, 12774.

110) “Design of Non-Cysteine-Containing Antimicrobial β-Hairpins:  Structure-Activity Relationship Studies with Linear Protegrin-1 Analogues,” J. R. L ai, B. R. Huck, B. Weisblum and S. H. Gellman Biochemistry 2002, 41, 12835.

109) “Stereoselective Synthesis of 3-Substituted 2-Aminocyclopentanecarboxylic Acid Derivatives and Their Incorporation into Short 12-Helical β-Peptides th at Fold in Water,” M. G. Woll, J. D. Fisk, P. R. LePlae and S. H. Gellman J. Am. Chem. Soc. 2002, 124, 12447.

108) “Synthesis and 12-Helical Secondary Structure of β-Peptides Containing (2R,3R)-Aminoproline,” E. A. Porter, X. Wang, M. A. Schmitt and S. H. Gellman Org. Lett. 2002, 4, 3317.

107) “Protein Prosthesis:  A Semisynthetic Enzyme with a β-Peptide Reverse Turn,” U. Arnold, M. P Hinderaker, B. L. Nilsson, B. R. Huck, S. H. Gellman and R. T. Raines J. Am. Chem. Soc. 2002, 124, 8522.

106) “Mimicry of Host-Defense Peptides by Unnatural Oligomers:  Antimicrobial β-Peptides,” E. A. Porter, B. Weisblum and S. H. Gellman J. Am. Chem. Soc. 2002, 124, 7324.

105) “Tolerance of Acyclic Residues in the β-Peptide 12-Helix:  Access to Diverse Sidechain Arrays for Biological Applications,” P. R. LePlae, J. D. F isk, E. A. Porter, B. Weisblum and S. H. Gellman J. Am. Chem. Soc. 2002, 124, 6820.

104) “Analysis of the Factors that Stabilize a Designed Two-Stranded Antiparallel β-Sheet,” J. F. Espinosa, F. A. Syud and S. H. Gellman Protein Sci. 2002, 11, 1492.

103) “Spectroscopic Characterization of Selected β-Sheet Hairpin Models,” J. Hilario, J. Kubelka, F. A. Syud, S. H. Gellman and T. A. Keiderling Biopolymers 2002, 67, 233.

102) “Translocation of a β-Peptide Across Cell Membranes,” N. Umezawa, M. A. Gelman, M. C. Haigis, R. T. Raines and S. H. Gellman J. Am. Chem. Soc. 2002, 124, 368.

101) “A Fluorescence Polarization Assay for the Identification of Inhibitors of the p53-DM2 Protein-Protein Interaction,” S. M. G. Knight, N. Umezawa, H.-S. Lee, S. H. Gellman and B. K. Kay, Anal. Biochem. 2002, 300, 230.

2001

100) “Toward β-Peptide Tertiary Structure:  Self-association of an Amphiphilic 14-Helix in Aqueous Solution,” T. L. Raguse, J. R. Lai, P. R. LePlae an d S. H. Gellman Org. Lett. 2001, 3, 3963.

99) “Parallel Sheet Secondary Structure in β-Peptides,” M. G. Woll, J. A. Lai, I. D. Guzei, S. J. C. Taylor, M. A. S. Smith and S. H. Gellman J. Am. Chem. Soc. 2001, 123, 11077.

98) “β-Peptides:  From Structure to Function,” R. P. Cheng, S. H. Gellman and W. F. DeGrado Chem. Rev. 2001, 101, 3219.

97) “Length-Dependent Stability and Strand Length Limits in Antiparallel β-Sheet Secondary Structure,” H. E. Stanger, F. A. Syud, J. F. Espinosa, I. G iriat, T. Muir and S. H. Gellman Proc. Natl. Acad. Sci. USA 2001, 98, 12015.

96) “Analysis of Interstrand Sidechain-Sidechain Contacts in a Designed β-Hairpin:  Significance of Both Lateral and Diagonal Interactions,” F. A. Syu d, H. E. Stanger and S. H. Gellman J. Am. Chem. Soc. 2001, 123, 8667.

95) “Diversity in Short β-Peptide 12-Helices:  High Resolution Structural Analysis in Aqueous Solution of a Hexamer Contraining Sulfonylated Pyrrolidine Re sidues,” H.-S. Lee, F. A. Syud, X. Wang and S. H. Gellman J. Am. Chem. Soc. 2001, 123, 7721.

94) “Evaluation of Hydrogen Bonding Complementarity Between a Secondary Sulfonamide and an β-Amino Acid Residue,” J. L. Langenhan, J. D. Fisk and S. H . Gellman Org. Lett. 2001, 3, 2559.

93) “An Efficient Route to Either Enantiomer of Trans-2-aminocyclopentanecarboxylic Acid,” P. R. LePlae, N. Umezawa, H.-S. Lee and S. H. Gellman J. Org. Chem . 2001, 66, 5629.

92) “An Efficient Route to Either Enantiomer of Orthogonally Protected Trans-3-Aminopyrrolidine-4-Carboxylic Acid,” H.-S. Lee, P. R. LePlae, E. A. Por ter and S. H. Gellman J. Org. Chem. 2001, 66, 3597.

91) “Beyond the Hydrophobic Effect:  Attractions Involving Heteroaromatic Rings in Aqueous Solution,” S. L. McKay, B. Haptonstall and S. H. Gellman J. Am. Ch em. Soc. 2001, 123, 1244.

90) “Interplay Between Hydrophobic Cluster and Loop Propensity in β-Hairpin Formation,” J. F. Espinosa, V. Muñoz and S. H. Gellman J. Mol. Biol. 2001, 306, 397.

89) “A Parallel β-Sheet Model System That Folds in Water,” J. D. Fisk and S. H. Gellman J. Am. Chem. Soc. 2001, 123, 343.

2000

88) “An Improved Tripod Amphiphile for Membrane Protein Solubilization,” S. M. Yu, D. T. McQuade, M. A. Quinn, C. P. R. Hackenberger, M. P. Krebs, A. S. Polans and S. H. Gellman Protein Sci. 2000, 9, 2518.

87) “Promotion of Sheet Formation in α-Peptide Strands by a β-Peptide Reverse Turn,” B. H. Huck, J. D. Fisk and S. H. Gel lman Org. Lett. 2000, 2, 2607.

86) “(R,R,R)-2,5-Diaminocyclohexanecarboxylic Acid, a Building Block for Water-Soluble, Helix-Forming β-Peptides,” D. H. Appella, P. R. LePlae, T. L. Raguse and S. H. Gellman J. Org. Chem. 2000, 65, 4766.

85) “Solvent-Dependent Stabilization of the E Configuration of Propargylic Secondary Amides,” R. R. Gardner, S. L. McKay and S. H. Gellman Org. Lett. 2000, 2, 2335.

84) “A Designed β-Hairpin Containing a Natural Hydrophobic Cluster,” J. F. Espinosa and S. H. Gellman Angew. Chem. Int. Ed. 2000, 39, 2330.

83) “Control of Hairpin Formation via Proline Configuration in Parallel β-Sheet Model Systems,” J. D. Fisk, D. R. Powell and S. H. Gellman J. Am. Chem. Soc. 2000, 122, 5443.

82) “12-Helix Formation in Aqueous Solution with Short β-Peptides Containing Pyrrolidine-Based Residues,” X. Wang, J. F. Espinosa and S. H. Gellman J. Am. Chem. Soc. 2000, 122, 4821.

81)  “Improved Treatment of Cyclic β-Amino Acids and Successful Prediction of β-Peptide Secondary Structure by a Modified Forc e Field:  AMBER*C,” L. A. Christianson, M. J. Lucero, D. H. Appella, D. A. Klein and S. H. Gellman J. Comp. Chem. 2000, 21, 763.

80) “Stereochemical Control of Hairpin Formation in β-Peptides Containing Dinipecotic Acid Reverse Turn Segments,” Y. J. Chung, B. H. Huck, L. A. Chri stianson, H. E. Stanger, S. Krauthäuser, D. R. Powell and S. H. Gellman J. Am. Chem. Soc. 2000, 122, 3995.

79) “Antibiotics:  Non-Haemolytic β-Amino Acid Oligomers,” E. A. Porter, X. Wang, H.-S. Lee, B. Weisblum and S. H. Gellman Natur e 2000, 404, 565.

78) “Solution Conformations of Helix-Forming β-Amino Acid Homooligomers,” J. J. Barchi, X. Huang, D. H. Appella, L. A. Christianson, S. R. Durell and S. H. Gellman J. Am. Chem. Soc. 2000, 122, 2711.

77) “Rigid Amphiphiles for Membrane Protein Manipulation,” D. T. McQuade, M. A. Quinn, S. M. Yu, A. S. Polans, M. P. Krebs and S. H. Gellman Angew. Chem. Int . Ed. 2000, 39, 758.

1999

76) “NMR-Based Quantification of β-Sheet Populations in Aqueous Solution Through Use of Reference Peptides for the Folded and Unfolded States,” F. A. Syud, J. F. Espinosa and S. H. Gellman J. Am. Chem. Soc. 1999, 121, 11577.

75) “Non-Hydrogen Bonded Secondary Structures in β-Peptides:  Evidence from Circular Dichroism of (S)-Pyrrolidine-3-Carboxylic Acid Oligomers and (S)-Nipecotic Acid Oligomers,” B. R. Huck, J. R. Langenhan and S. H. Gellman Org. Lett. 1999, 1 , 1717.

74) “Synthesis and Characterization of Helix-Forming β-Peptides:  trans-2-aminocyclopentanecarboxylic acid oligomers,” D. H. Appella, L. A. Christianson, D. A. Klein, M. R. Richards, D. R. Powell and S. H. Gellman J. Am. Chem. Soc. 1999, 121, 7574.

73) “Synthesis and Characterization of trans-2-Aminocyclohexanecarboxylic Acid Oligomers:  An Unnatural Secondary Structure, and Implications for β-Peptide Tertiary Structure,” D. H. Appella, L. A. Christianson, I. L. Karle, D. R. Powell and S. H. Gellman J. Am. Chem. Soc. 1999, 121, 6206.

72) “Comparison of an HXH Three-Center Hydrogen Bond with Alternative Two-Center Hydrogen Bonds in a Model System,” J. Yang, L. A. Christianson and S. H. Gellman Org. Lett. 1999, 1, 11.

71)  “A Fluorescence Assay for Leucine Zipper Dimerization:  Avoiding Unintended Consequences of Fluorophore Attachment,” D. L. Daugherty and S. H. Gellman J . Am. Chem. Soc. 1999, 121, 4325.

70) “Short, Stable Helices in Aqueous Solution from β-Amino Acid Hexamers,” D. H. Appella, J. J. Barchi, S. R. Durell and S. H. Gellman J. Am. Chem. Soc. 1999, 121, 2309.

69) “β-Turn and β-Hairpin Mimicry with Tetrasubstituted Alkenes,” R. R. Gardner, G.-B. Liang and S. H. Gellman J. Am. Chem. Soc. 1999, 121, 1806.

1998

68) “Artificial Chaperone-Assisted Refolding of Citrate Synthase,” D. L. Daugherty, D. Rozema, P. E. Hanson and S. H. Gellman J. Biol. Chem. 1998, 273, 33961.

67)  “Mechanistic Comparison of Artificial Chaperone-Assisted and Unassisted Refolding of Urea-Denatured Carbonic Anhydrase B,” P. E. Hanson and S. H. Gellman Folding & Design 1998, 3, 457.

66)  “Minimal model systems for β-sheet secondary structure in proteins,” S. H. Gellman Curr. Opin. Chem. Biol. 1998, 2, 717.

65) “A β-Peptide Reverse Turn that Promotes Hairpin Formation,” Y. J. Chung, L. A. Christianson, H. E. Stanger, D. R. Powell and S. H. Gellman J. Am. Chem. Soc. 1998, 120, 10555.

64) “Energetic Superiority of Two-Center Hydrogen Bonding Relative to Three-Center Hydrogen Bonding in a Model System,” J. Yang and S. H. Gellman J. Am. Chem . Soc. 1998, 120, 9090.

63) “Theoretical and Experimental Circular Dichroic Spectra of the Novel Helical Foldamer Poly[(1R,2R)-trans-2-aminocyclopentanecarboxylic acid],” J. Applequist, K. A. Bode, D. A. Appella, L. A. Christianson and S. H. Gellman J. Am. Chem. Soc. 1998, 120, 4891.

62) “Use of a Designed Triple-Stranded Antiparallel β-Sheet to Probe β-Sheet Cooperativity in Aqueous Solution,” H. L. Sc henck and S. H. Gellman J. Am. Chem. Soc. 1998, 120, 4869.

61) “Rules for Antiparallel β-Sheet Design:  D-Pro-Gly is Superior to L-Asn-Gly for β-Hairpin Nucleation,” H. E. Stanger and S. H. Gellman J. Am. Chem. Soc. 1998, 120, 4236.

60) “Foldamers:  A Manifesto,” S. H. Gellman Acc. Chem. Res. 1998, 31, 173.

1997

59) “Antiparallel Sheet Formation in β-Peptide Foldamers:  Effects of β-Amino Acid Substitution on Conformational Preference, ” S. Krauthäuser, L. A. Christianson, D. R. Powell and S. H. Gellman J. Am. Chem. Soc. 1997, 119, 11719.

58) “Steric Control of Oxidation Selectivity in Macrocyclic Phosphine Oxide-Dithioethers,” S. K. Holmgren, P. B. Savage, J. M. Desper, K. D. Schladetzky, D. R. Powell and S. H. G ellman  Tetrahedron 1997, 53, 12249 (Symposium-in-Print on “Recent Aspects of S, Se and Te Chemistry”).

57) “Indifference to Hydrogen Bonding in a Family of Secondary Amides,” D. T. McQuade, S. L. McKay, D. R. Powell and S. H. Gellman J. Am. Chem. Soc. 1997, 119, 8528.

56) “Secondary Effects in Flexible Hydrogen Bonding Networks,” R. R. Gardner and S. H. Gellman, Tetrahedron  1997, 53, 9881 (issue in honor of William Doering’s 80th birthday).

55) “Quantitative Analysis of Hydrophobically Induced Folding in a Minimal Model System,” R. R. Gardner, L. A. Christianson and S. H. Gellman J. Am. Chem. S oc. 1997, 119, 5041.

54) “Residue-Based Control of Helix Shape in β-Peptide Oligomers,” D. H. Appella, L. A. Christianson, D. Klein, D. R. Powell, X. Huang, J. J. Barchi and S. H. Gellman Nature 1997, 387, 381.

53) “Insights on β-Hairpin Stability in Aqueous Solution from Peptides with Enforced Type I’ and Type II’ β-Turns,” T. S. Haque and S. H. Gellman J. Am. Chem. Soc. 1997, 119 , 2303.

1996

52) “(Z)-2-(Benzoyl-aci-nitro)-2-phenylacetonitrile,” D. R. Powell, P. E. Hanson and S. H. Gellman Acta Cryst. 1996, C52, 2945.

51) “New Evidence that the Hydrophobic Effect and Dispersion are not Major Driving Forces for Nucleotide Stacking,” S. H. Gellman, T. S. Haque and L. F. Newcomb Biophys. J. 1996, 71, 3523.

50) “β-Peptide Foldamers:  Robust Helix Formation in a New Family of β-Amino Acid Oligomers,” D. H. Appella, L. A. Chris tianson, I. L. Karle, D. R. Powell and S. H. Gellman J. Am. Chem. Soc. 1996, 118, 13071.

49) “Redox-Triggered Secondary Structure Changes in the Aggregated States of a Designed Methionine-Rich Peptide,” H. L. Schenck, G. P. Dado and S. H. Gellman J. Am. Chem. Soc. 1996, 118, 12487.

48) “Artificial Chaperone-Assisted Refolding of Denatured-Reduced Lysozyme:  Modulation of the Competition Between Renaturation and Aggregation,” D. Rozema and S. H. Gellman Biochemistry 1996, 35, 15760.

47) “Stereochemical Requirements for β-Hairpin Formation:  Model Studies with Four-Residue Peptides and Depsipeptides,” T. S. Haque, J. L. Little and S. H. Gellman J. Am. Chem. Soc. 1996, 118, 6975.

46) “Artificial Chaperone-Assisted Refolding of Carbonic Anhydrase B,” D. Rozema and S. H. Gellman J. Biol. Chem. 1996, 271, 3478.

1995

45) “Evaluation of the Conformation-Directing Effects of Secondary Hydrogen Bonding Interactions in Flexible Tetrapeptide Analogues,” R. R. Gardner and S. H. Gellman J. Am. Chem. Soc. 1995, 117, 10411.

44) “Searching for Minimum Increments of Hydrophobic Collapse:  Flexible Dinaphthyl Carboxylates,” L. F. Newcomb, T. S. Haque and S. H. Gellman J. Am. Chem. Soc. 1995, 117, 6509.

43) “Structural Characterization of Thiocyclophanes that Promote Edge-to-Face Aromatic-Aromatic Geometries,”  K. D. Schladetzky, T. S. Haque and S. H. Gellman J. Org. Chem. 1995, 60, 4108.

42) “Effects of Amphiphilic Topology on Self-Association in Solution, at the Air-Water Interface, and in the Solid State,” D. T. McQuade, D. G. Barrett, J. M. Desper, R. K. Hayas hi and S. H. Gellman J. Am. Chem. Soc. 1995, 117, 4862.

41) “An Achiral Dipeptide Mimetic that Promotes β-Hairpin Formation,” R. Gardner, G.-B. Liang and S. H. Gellman J. Am. Chem. So c. 1995, 117, 3280.

40) “Artificial Chaperones:  Protein Refolding via Sequential Use of Detergent and Cyclodextrin,” D. Rozema and S. H. Gellman J. Am. Chem. Soc. 1995, 117, 2373.

1994

39) “The Effect of a C-Terminal Cationic Group on the Competition Between α-Helical Turn and β-Turn in a Model Depsipeptide,& quot; E. A. Gallo and S. H. Gellman J. Am. Chem. Soc. 1994, 116, 11560.

38) “Synthetic Studies on the 1,6-Methano[10]annulene Skeleton:  A New Route that Provides Derivatives Substituted at the Bridge and on the Annulene Ring,” D. G. Barrett, G.-B. L iang, D. T. McQuade, J. M. Desper, K. D. Schladetzky and S. H. Gellman J. Am. Chem. Soc. 1994, 116, 10525.

37) “Aromatic Stacking Interactions in Aqueous Solution:  Evidence that Neither Classical Hydrophobic Effects nor Dispersion Forces are Involved,” L. F. Newcomb and S. H. Gellman J. Am. Chem. Soc. 1994, 116, 4993.

36) “‘Mirror Image’ Reverse Turns Promote β-Hairpin Formation,” T. S. Haque, J. C. Little and S. H. Gellman J. Am. Chem. Soc.1994, 116, 4105.

35) “Anion and Ion Pair Complexation by a Macrocyclic Phosphine Oxide Disulfoxide,” P. B. Savage, S. K. Holmgren and S. H. Gellman J. Am. Chem. Soc. 1994, 116, 4069.

34) “Electrophile-Induced Berson-Willcott Rearrangement of 11-Carboxyl-1,6-Methano[10]annulene Methyl Ester,” D. G. Barrett and S. H. Gellman Tetrahedron Le tt. 1994, 35, 2299.

33) “On the Hydrogen Bonded Status of 2-Azacyclononanone and 2-Azacyclotridecanone in the Solid State,” R. D. Skwiercyznski and S. H. Gellman J. Phys. Chem. 1994, 98, 3694.

32) “Strategies for Nonmacrocyclic Polythioether Ligands:  New Pentacoordinating Architectures,” J. M. Desper and S. H. Gellman Angew. Chem. Int. Ed. Engl.< /span> 1994, 33, 319.

31) “Intramolecular Hydrogen Bonding in Derivatives of β-Alanine and γ-Amino Butyric Acid:  Model Studies for the Folding of Unnatural Polypeptide Backbones,” G. P. Dado and S. H. Gellman J. Am. Chem. Soc. 1994, 116, 1054.

1993

30) “Redox-Controlled Secondary Structure Switching in a Designed Peptide,” G. P. Dado and S. H. Gellman J. Am. Chem. Soc. 1993 , 115, 12609.

29) “Complexation of Hexosammonium ions:  Evidence for Contributions from OH–OH Hydrogen Bonds in a Hydroxylic Medium,” P. B. Savage and S. H. Gellman J. A m. Chem. Soc. 1993, 115, 10448.

28) “Hydrogen Bond-Mediated Folding in Depsipeptide Models of β-Turns and α-Helical Turns,” E. A.Gallo and S. H. Gellman J. Am. Chem. Soc. 1993, 115, 9774.

27) “Effects of Amphiphile Topology on Aggregation Properties:  Distinctive Behavior of Contrafacial Amphiphiles,” D. G. Barrett and S. H. Gellman J. Am. Ch em. Soc., 1993, 115, 9343.

26) “Optimization of a Phosphine Oxide-Disulfoxide Array for Multipoint Hydrogen Bonding to Ammonium Ions,” P. B. Savage, S. K. Holmgren and S. H. Gellman J . Am. Chem. Soc. 1993, 115, 7900.

25) “Structural and Thermodynamic Characterization of Temperature-Dependent Changes in the Folding Pattern of a Synthetic Triamide,” G. P. Dado and S. H. Gellman J. Am. Chem. Soc. 1993, 115, 4228.

24) “Nickel(II) Chelation by Three Bicyclic Tetrathioethers:  Solution and Solid State Data,” J. M. Desper, J. R. Vyvyan, M. J. Mayer, L. A. Ochrymowycz and S. H. Gellman Inorg. Chem. 1993, 32, 3 81.

23) “Macrocycles Containing Sulfur and Phosphorus:  Structure and Complexation Properties,” P. B. Savage, S. K. Holmgren, J. M. Desper and S. H. Gellman Pur e Appl. Chem. 1993, 65, 461.

22) “Effects of Backbone Rigidification on Intramolecular Hydrogen Bonding in a Family of Diamides,”  G.-B. Liang, J. M. Desper and S. H. Gellman J. Am. Chem. Soc. 1993, 115, 925.

1992

21) “N-H–π Hydrogen Bonding in a Norbornenyl Diamide,” E. A. Gallo and S. H. Gellman Tetrahedron Lett. 1992, 33, 7485.

20) “Thermodynamics of Copper(II) Complexation by Macrocyclic Tetrathioethers at 25oC in Water-Methanol Mixtures and Acetonitrile:  Correlations of Comple xation Enthalpy and Ligand Conformational Preferences,”  A. Z. Nazarenko, R. M. Izatt, J. D. Lamb, J. M. Desper, B. E. Matysik and S. H. Gellman Inorg. Chem. 1992, 31, 3990.

19) “A New Synthesis of Methano-Bridged Annulenes:  Access to Highly Substituted Derivatives,” D. G. Barrett, G.-B. Liang and S. H. Gellman J. Am. Chem. Soc . 1992, 114, 6915.

18) “Effects of Covalent Modifications on the Solid State Folding and Packing of N-Malonyl-Glycine Derivatives,” G. P. Dado, J. M. Desper, S. K. Holmgren, C. J. Rito and S. H. Ge llman J. Am. Chem. Soc. 1992, 114, 4834.

17) “Thermodynamic Analysis of β-Turn Formation in Pro-Ala, Pro-Gly and Pro-Val Model Peptides in Methylene Chloride,” G.-B. Liang, C. J. Rito and S. H. Gellman J. Am. Chem. Soc. 1992, 114, 4440.

16) “Synthesis and Aggregation Properties of a New Family of Amphiphiles with an Unusual Headgroup Topology,” T. M. Stein and S. H. Gellman J. Am. Chem. Soc . 1992, 114, 3943.

15) “Stereoselective Oxidation of an Eleven-Membered Heterocycle,” P. B. Savage, J. M. Desper and S. H. Gellman Tetrahedron Lett. 1992, 33, 2107.

14) “An Unusual Hydrogen Bonding Pattern in a Crystallographically Observed β-Turn,” S. H. Gellman, D. R. Powell and J. M. Desper Tetrahedron Lett. 1992, 33, 1963.

13) “On the Use of AM1 Calculations for the Study of Intramolecular Hydrogen Bonding Phenomena in Simple Amides,” G. P. Dado and S. H. Gellman J. Am. Chem. Soc. 1992, 114, 3138.

12) “Variations in the Turn-Forming Characteristics of N-Acyl Proline Units,” G.-B. Liang, C. J. Rito and S. H. Gellman Biopolymers, 1992, 32, 293.

1991

11) “On the Use of Molecular Mechanics Calculations for the Study of Intramolecular Hydrogen Bonding Phenomena,” S. H. Gellman and G. P. Dado Tetrahedron Le tt. 1991, 32, 7377.

10) “Enhanced Ni(II) Chelation by gem-Dimethyl-Substituted Macrocyclic Tetrathioethers,” J. M. Desper, S. H. Gellman, R. E. Wolf, and S. R. Cooper J. Am. Chem. Soc. 1991, 113, 8663.

9) “On the Role of Methionine Residues in the Sequence-Independent Recognition of Non-Polar Protein Surfaces,” S. H. Gellman Biochemistry  1991, 30, 6633.

8) “Anatomy of a Stable Intramolecularly Hydrogen Bonded Folding Pattern,” G.-B. Liang, G. P. Dado and S. H. Gellman J. Am. Chem. Soc. 1991, 113, 3994.

7) “Conformation-Directing Effects of a Single Intramolecular Amide-Amide Hydrogen Bond:  Variable Temperature NMR and IR Studies on a Homologous Diamide Series,” S. H. Gellman, G. P. Dado, G.-B. Liang and B. R. Adams J. Am. Chem. Soc. 1991, 113, 1164.

6) “Crystallographic Evidence for Multiple Coordinating Conformations in a Family of Macrocyclic Chelators,”  J. M. Desper and S. H. Gellman J. Am. Chem. So c. 1991, 113, 704.

1990

5) “Hydrogen Bonding in a Family of Triamides:  Conformation-Directing Effects in Solution vs. the Solid State,” G. P. Dado, J. M. Desper and S. H. Gellman J. Am. Chem. Soc. 1990, 112, 8630.

4) “Incremental Preorganization of a Chelating Macrocycle,” J. M. Desper and S. H. Gellman J. Am. Chem. Soc. 1990, 112, 6732.

3) “The Molecular Structure and Conformation of Two Acyclic Polythioethers:  Implications for the Design of Heavy Metal Chelators,”  J. M. Desper, D. R. Powell and S. H. Gellman J. Am. Chem. Soc. 1990, 112, 4321.

2) “Temperature-Dependent Changes in the Folding Pattern of a Simple Triamide,” S. H. Gellman, B. R. Adams and G. P. Dado, J. Am. Chem. Soc. 1990, 112, 460.

1989

1) “Intramolecular Hydrogen Bonding in Simple Diamides,” S. H. Gellman and B. R. Adams Tetrahedron Lett. 1989, 30, 3381.