Publications - 2014

303) “New charge-bearing amino acid residues that promote β-sheet secondary structure." Maynard SJ, Almeida AM, Yoshimi Y, Gellman SH J. Am. Chem. Soc. 2014136, 16683.

302) “A γ-amino acid that favors 12/10-helical secondary structure in α/γ-peptides." Giuliano MW, Maynard SJ, Almeida AM, Guo L, Guzei IA, Spencer LC, Gellman SH J. Am. Chem. Soc. 2014136, 15046.

301) “Synthetic polymers active against Clostridium difficile vegetative cell growth and spore outgrowth." Liu R, Suárez JM, Weisblum B, Gellman SH, McBride SM J. Am. Chem. Soc. 2014136, 14498.

300) “Ternary nylon-3 copolymers as host-defense peptide mimics: beyond hydrophobic and cationic subunits." Chakraborty S, Liu R, Hayouka Z, Chen X, Ehrhardt J, Lu Q, Burke E, Yang Y, Weisblum B, Wong GC, Masters KS, Gellman SH J. Am. Chem. Soc. 2014136, 14530.

299) “A potent α/β-peptide analogue of GLP-1 with prolonged action in vivo." Johnson LM, Barrick S, Hager MV, McFedries A, Homan EA, Rabaglia ME, Keller MP, Attie AD, Saghatelian A, Bisello A, Gellman SH J. Am. Chem. Soc. 2014136​, 12848.

298) “Medium effects on minimum inhibitory concentrations of nylon-3 polymers against E. coli." Choi H, Chakraborty S, Liu R, Gellman SH, Weisshaar JC PLoS One 20149, e104500.

297) “Backbone modification of a polypeptide drug alters duration of action in vivo.” Cheloha RW, Maeda A, Dean T, Gardella TJ, Gellman SH. Nat Biotechnol. 2014 ,32, 653.

296) “Hydrophobicity and Helicity Regulate the Antifungal Activity of 14-Helical β-Peptides.” Lee MR, Raman N, Gellman SH, Lynn DM, Palecek SP. ACS Chem Biol. 20149, 1613.

295) “Building Proficient Enzymes with Foldamer Prostheses.” Mayer C, Müller MM, Gellman SH, Hilvert D. Angew Chem Int Ed Engl. 2014, 53, 6978.

294) “Two interdependent mechanisms of antimicrobial activity allow for efficient killing in nylon-3-based polymeric mimics of innate immunity peptides.” Lee M, Chakraborty S, Schmidt NW, Murgai R, Gellman SH, Wong GC. Biochim Biophys Acta. 2014, 1838, 2269.

293) “Improved Glucose-Neopentyl Glycol (GNG) Amphiphiles for Membrane Protein Solubilization and Stabilization.” Cho KH, Bae HE, Das M, Gellman SH, Chae PS.Chem Asian J. 20149, 632.

292) “Mimicking the First Turn of an α-Helix with an Unnatural Backbone: Conformation-Specific IR and UV Spectroscopy of Cyclically Constrained β/γ-Peptides.” Gord JR, Walsh PS, Fisher BF, Gellman SH, Zwier TS. J Phys Chem B2014, 118, 8246.

291) "Structure–Activity Relationships among Antifungal Nylon-3 Polymers: Identification of Materials Active against Drug-Resistant Strains of Candida albicans." Liu R, Chen X, Falk SP, Mowery BP, Karlsson AJ, Weisblum B, Palecek SP, Masters KS, Gellman SH., J Am Chem Soc. 2014136, 4333.

290) "Tuning the Biological Activity Profile of Antibacterial Polymers via Subunit Substitution Pattern." Liu R, Chen X, Chakraborty S, Lemke JJ, Hayouka Z, Chow C, Welch RA, Weisblum B, Masters KS, Gellman SH., J Am Chem Soc. 2014136, 4410.

289) “Hydrophobic variants of ganglio-tripod amphiphiles for membrane protein manipulation”Chae PS, Cho KH, Wander MJ, Bae HE, Gellman SH, Laible PD, Biochim Biophys Acta.20141838, 278.

288) “Two-dimensional sum-frequency generation reveals structure and dynamics of a surface-bound Peptide.” Laaser JE, Skoff DR, Ho JJ, Joo Y, Serrano AL, Steinkruger JD, Gopalan P, Gellman SH, Zanni MT. J Am Chem Soc. 2014136, 956.

287) “Hydrophobic Variations of N-Oxide Amphiphiles for Membrane Protein Manipulation: Importance of Non-hydrocarbon Groups in the Hydrophobic Portion.” Chae PS, Sadaf A, Gellman SH., Chem Asian J. 20149, 110.