Publications - 2008

206) "Synthesis of β-Lactams Bearing Functionalized Side Chains from a Readily Available Precursor," M.-r. Lee, S. S. Stahl and S. H. Gellman Org. Lett. 2008, 10, 5317.

205) "Mechanical Stability of Helical β-Peptides and a Comparison of Explicit and Implicit Solvent Models," C. A. Miller, S. H. Gellman, N. L. Abbott, J. J. de Pablo Biophys. J. 2008, 95, 3123.

204) "Characterization of Nanofibers Formed by Self-Assembly of β-Peptide Oligomers Using Small Angle X-Ray Scattering," C. L. Pizzery, W. C. Pomerant z, B.-J. Sung, V. M. Yuwono, J. D. Hartgerink, S. H. Gellman, A. Yethiraj and N. L. Abbott J. Chem. Phys. 2008, 129, 095103.

203) "Foldamers with Heterogeneous Backbones," W. S. Horne and S. H. Gellman Acc. Chem. Res. 2008, 41, 1399.

202) "Comparison of Design Strategies for Promotion of β-Peptide 14-Helix Stability in Water," E. Vaz, W. C. Pomerantz,  M. Geyer, S. H. Gellman and L . Brunsveld ChemBioChem 2008, 9, 2254.

201) "Glycotripod Amphiphiles for Solubilization and Stabilization of a Membrane Protein Superassembly:  Importance of Branching in the Hydrophilic Portion," P. S. Chae, M. J. Wan der, A. P. Bowling, P. D. Laible and S. H. Gellman ChemBioChem 2008 9, 1706.

200) "Interplay Among Side Chain Sequence, Backbone Composition and Residue Rigidification in Polypeptide Folding and Assembly," W. S.  Horne, J. L. Price and S. H. Gellman Proc. Natl. Acad. Sci. USA 2008, 105, 9151.

199) "Dipole-Induced Self-Assembly of Helical β-Peptides," C. A. Miller, J. P. Hernández-Ortiz, N. L. Abbott, S. H. Gellman and J. J. de Pablo J. Chem. Phys. 2008, 129, 015102.

198) "Diacid Linkers that Promote Parallel β-Sheet Secondary Structure in Water," F. Friere, J. D. Fisk, A. J. Peoples, M. Invancic, I. A. Guzei and S . H. Gellman J. Am. Chem. Soc. 2008, 130, 7839.

197) "Hydrophile-Scanning as a Complement to Alanine-Scanning for Exploring and Manipulating Protein-Protein Recognition:  Application to the Bim BH3 Domain," M. D. Boersma, J. D. Sadowsky, Y. Tomita and S. H. Gellman Protein Sci. 2008, 17, 1232.

196) "Inhibition of Herpes Simplex Virus Type 1 Infection by Cationic β-Peptides," R. Akkarawongsa, T. B. Potocky, E. English, S. H. Gellman and C. R. Brandt Antimicrob. Agents Chemother. 2008, 52, 2120.

195) "Dual Mechanism of Bacterial Lethality for a Cationic Sequence-Random Copolymer that Mimics Host-Defense Antimicrobial Peptides," R. F. Epand, B. P. Mowery, S. E. Lee, S. S. Stahl, R. I. Lehrer, S. H. Gellman and R. M. Epand J. Mol. Biol. 2008, 379, 38.

194) "A Fluorescence Polarization Assay for Identifying Ligands that Bind to Vascular Endothelial Growth Factor," K. J. Peterson, J. D. Sadowsky, E. A. Scheef, S. Pal, K. D. Koure ntzi, R. C. Willson, E. H. Bresnick, N. Sheibani and S. H. Gellman Anal. Biochem. 2008, 378, 8.

193) "Distinctive Circular Dichroism Signature for 14-Helix-Bundle Formation by β-Peptides," W. C. Pomerantz, T. L. R. Grygiel, J. R. Lai and S. H. Ge llman Org. Lett. 2008, 10, 1799.

192) "Crystallographic Characterization of Helical Secondary Structures in α/β-Peptides with 1:1 Residue Alternation," S. H. Choi, I. Guzei, L. Spence r and S. H. Gellman J. Am. Chem. Soc. 2008, 130, 6544.

191) "Enantioselective Organocatalytic Michael Addition of Aldehydes to Nitroethylene:  Efficient Access to γ2-Amino Acids,&qu ot; Y. Chi, L. Guo, N. Kopf and S. H. Gellman  J. Am. Chem. Soc.  2008, 130, 5608.

190) "Establishing Effective Simulation Protocols for β- and α/β-Peptides. II. Molecular Mechanical (MM) Model for a Cyclic β-Residue," X. Zhu, P. Koenig, S. H. Gellman, A. Yethiraj,  C. Qiang J. Phys. Chem. B 2008, 112, 5439.

189) "Single-Conformation Ultraviolet and Infrared Spectroscopy of Model Synthetic Foldamers:  β-Peptides Ac-β3-hPhe-β3-hAla-NHMe and Ac-β3-hAla-β3-hPhe-NHMe,& quot; E. E. Baquero, W. H. James III, S. H. Choi, S. H. Gellman and T. S. Zwier  J. Am. Chem. Soc. 2008, 130, 4795.

188) "Single-Conformation Ultraviolet and Infrared Spectroscopy of Model Synthetic Foldamers:  β-Peptides Ac-β3-hPhe-NHMe and Ac-β3-hTyr-NHMe," E. E. Baquero, W. H. James III, S. H. Choi, S. H. Gellman and T. S. Zwier  J. Am. Chem. Soc. 2008, 130, 4784.

187) "Sequence-Based Design of α/β-Peptide Foldamers that Mimic α-Helical BH3 Domains," W. S. Horne, M. D. Boersman, M. A . Windsor and S. H. Gellman Angew. Chem. Int. Ed. 2008, 47, 2853.

186) "Exploration of Structure/Activity Relationships among Foldamer Ligands for a Specific Protein Binding Site via Parallel and Split-and-Mix Library Synthesis," J. K. Murray, J . D. Sadowsky, M. Scalf, L. M. Smith, Y. Tomita and S. H. Gellman J. Combi. Chem. 2008, 10, 204.

185) "Nanofibers and Lyotropic Liquid Crystals from a New Class of Self-Assembling β-Peptides," W. C. Pomerantz, V. M. Yuwono, C. L. Pizzey, J. D. Har tgerink, N. L. Abbott and S. H. Gellman Angew. Chem. Int. Ed. 2008, 47, 1241.

184) "Preferred Side-chain Constellations at Antiparallel Coiled-coil Interfaces," E. B. Hadley, O. D. Testa, D. N. Woolfson and S. H. Gellman Proc. Natl. Ac ad. Sci. USA 2008, 105, 530.

183) "Discovery and Mechanistic Study of AlIII-Catalyzed Transamidation of Tertiary Amides," J. M. Hoerter, K. M. Otte, S. H. Gellman, Q. Cui and S. S . Stahl J. Am. Chem. Soc. 2008, 130, 647.