Publications - 2007

182) "Mimicry of Antimicrobial Host-Defense Peptides by Random Co-Polymers," B. P. Mowery, S. E. Lee, D. A. Kissounko, R. F. Epand, R. M. Epand, B. Weisblum, S. S. Stahl and S. H. Gellman J. Am. Chem. Soc. 2007, 129, 15474.

181) "Crystallographic Characterization of the α/β-Peptide 14/15-Helix," S. H. Choi, I. A. Guzei and S. H. Gellman J. Am. Chem. Soc. 2007, 129, 13780.

180) "Thermodynamic Analysis of β-Sheet Secondary Structure Via Backbone Thioester Exchange," E. B. Hadley, A. M. Witek, F. Friere, A. J. Peoples and S. H. Gellman Angew. Chem. Int. Ed. 2007, 46, 7056.

179) "Targeting Protein-Protein Interactions:  Lessons from p53/MDM2," J. K. Murray and S. H. Gellman, Biopol. - Pept.  Sci. 200 7, 88, 657.

178) "Sequence Dependent Behavior of Amphiphilic β-Peptides on Gold Surfaces," W. C. Pomerantz, K. D. Cadwell, Y.-J. Hsu, S. H. Gellman and N. L. Abbo tt  Chem. Materials 2007, 19, 4436.

177) "H/D Exchange- and Mass Spectrometry-Based Strategy for the Thermodynamic Analysis of Protein-Ligand Binding," L. Tang, E. D. Hopper, Y. Tong, J. D. Sadowsky, K. J. Peterson, S. H. Gellman and M. C. Fitzgerald Anal. Chem. 2007, 79, 5869.

176) "Discrete Heterogeneous Quaternary Structure Formed by α/β-Peptide Foldamers and α-Peptides," J. L. Price, W. S. Hor ne and S. H. Gellman J. Am. Chem. Soc. 2007, 129, 6376.

175) "HeLa Cell Entry by Guanidinium-Rich β-Peptides:  Importance of Specific Cation-Cell Surface Interactions," T. B. Potocky, J. Silvius, A. K. Meno n and S. H. Gellman ChemBioChem 2007, 8, 917.

174) "Exploration of Backbone Space in Foldamers Containing α- and β-Amino acid Residues: Application to Developing Protease-R esistant Oligomers that Bind Tightly to the BH3-Recognition Cleft of Bcl-xL," J. D. Sadowsky, J. K. Murray, Y. Tomita and S. H. Gellman ChemBioChem 200 7, 8, 903.

173) "Practical Synthesis of Enantiomerically Pure β2-Amino Acids via Proline-Catalyzed Diastereoselective Aminomethylation of Aldehydes," Y. Chi, E. P. English, W. C. Pomerantz, W. S. Horne, L. A. Joyce, L. R. Alexander, W. S. Fleming, E. A. Hopkins and S. H. Gellman J. Am. Chem. Soc. 2007, 129, 6050.

172) "Origins of the High 14-Helix Propensity of Cycohexyl-Rigidified Residues in β-Peptides," M. Lee, T. L. Raguse, M. Schinnerl, W. C. Pomerantz, X. Wang, P. Wipf and S. H. Gellman Org. Lett. 2007, 9, 1801.

171) "Helix-Bundle Quaternary Structure from α/β-Peptide Foldamers," W. S. Horne, J. L. Price, J. L. Keck and S. H. Gellman J. A m. Chem. Soc. 2007, 129, 4178.

170) "Parallel Synthesis of Peptide Libraries Using Microwave Irradiation," J. K. Murray and S. H. Gellman, Nat.  Protocols 2007 , 2, 624.

169) "TiIV-Mediated Reactions between Primary Amines and Secondary Carboxamides: Amidine Formation Versus Transamidation," D. A. Kissounko, J. M. Hoer ter, I. A. Guzei, Q. Cui, S. H. Gellman and S. S. Stahl J. Am. Chem. Soc. 2007, 129, 1776.

168) "Catalytic Metathesis of Simple Secondary Amides," C. M. Bell, D. A. Kissounko, S. H. Gellman and S. S. Stahl Angew. Chem. Int. Ed. 2007, 46, 761.

167) "Interplay Among Folding, Sequence, and Lipophilicity in the Antibacterial and Hemolytic Activities of α/β-Peptides," M. A. Schmitt, B. Weisblum and S. H. Gellman J. Am. Chem. Soc. 2007, 129, 417.

166) "(α/β +α)-Peptide Antagonists of BH3 Domain/Bcl-xL Recognition:  Toward General Strategies f or Foldamer-Based Inhibition of Protein-Protein Interactions," J. D. Sadowsky, W. D. Fairlie, E. B. Hadley, H.-S. Lee, N. Umezawa, Z. Nikolovska-Coleska, S. Wang, D. C. S. Huang, Y. Tomita and S. H. Gellman  J . Am. Chem. Soc. 2007, 129, 139.

165)  "Solution Structure of a Small Protein Containing a Fluorinated Side Chain in the Core," G. Cornilescu, E. B. Hadley, M. G. Woll, J. L. Markley, S. H. Gellman and C. C. Corn ilescu Protein Sci. 2007, 16, 14.