Publications - 2002

112) "Evidence that the β-Peptide 14-Helix is Stabilized by β3-Residues with Sidechain Branching Adjacent to the β-Carbon,” T. R. Raguse, J. R. Lai and S. H. Gellman, Helv. Chim. Acta 2002, 85, 4154 (issue in honor of the 65th birthday of D. Seebach).

111) "Structure-Activity Studies of 14-Helical Antimicrobial β-Peptides:  Probing the Relationship Between Conformational Stability and Antimicrobial Poten cy," T. R. Raguse, E. A. Porter, B. Weisblum and S. H. Gellman J. Am. Chem. Soc. 2002, 124, 12774.

110) "Design of Non-Cysteine-Containing Antimicrobial β-Hairpins:  Structure-Activity Relationship Studies with Linear Protegrin-1 Analogues," J. R. L ai, B. R. Huck, B. Weisblum and S. H. Gellman Biochemistry 2002, 41, 12835.

109) "Stereoselective Synthesis of 3-Substituted 2-Aminocyclopentanecarboxylic Acid Derivatives and Their Incorporation into Short 12-Helical β-Peptides th at Fold in Water," M. G. Woll, J. D. Fisk, P. R. LePlae and S. H. Gellman J. Am. Chem. Soc. 2002, 124, 12447.

108) "Synthesis and 12-Helical Secondary Structure of β-Peptides Containing (2R,3R)-Aminoproline," E. A. Porter, X. Wang, M. A. Schmitt and S. H. Gellman Org. Lett. 2002, 4, 3317.

107) "Protein Prosthesis:  A Semisynthetic Enzyme with a β-Peptide Reverse Turn," U. Arnold, M. P Hinderaker, B. L. Nilsson, B. R. Huck, S. H. Gellman and R. T. Raines J. Am. Chem. Soc. 2002, 124, 8522.

106) "Mimicry of Host-Defense Peptides by Unnatural Oligomers:  Antimicrobial β-Peptides," E. A. Porter, B. Weisblum and S. H. Gellman J. Am. Chem. Soc. 2002, 124, 7324.

105) "Tolerance of Acyclic Residues in the β-Peptide 12-Helix:  Access to Diverse Sidechain Arrays for Biological Applications," P. R. LePlae, J. D. F isk, E. A. Porter, B. Weisblum and S. H. Gellman J. Am. Chem. Soc. 2002, 124, 6820.

104) "Analysis of the Factors that Stabilize a Designed Two-Stranded Antiparallel β-Sheet," J. F. Espinosa, F. A. Syud and S. H. Gellman Protein Sci. 2002, 11, 1492.

103) "Spectroscopic Characterization of Selected β-Sheet Hairpin Models," J. Hilario, J. Kubelka, F. A. Syud, S. H. Gellman and T. A. Keiderling Biopolymers 2002, 67, 233.

102) "Translocation of a β-Peptide Across Cell Membranes," N. Umezawa, M. A. Gelman, M. C. Haigis, R. T. Raines and S. H. Gellman J. Am. Chem. Soc. 2002, 124, 368.

101) "A Fluorescence Polarization Assay for the Identification of Inhibitors of the p53-DM2 Protein-Protein Interaction," S. M. G. Knight, N. Umezawa, H.-S. Lee, S. H. Gellman and B. K. Kay, Anal. Biochem. 2002, 300, 230.